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A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis.
Br J Dermatol. 1996 Jul; 135(1):86-8.BJ

Abstract

We report a randomized, double-blind study, comparing the relative efficacy and tolerability of oral terbinafine, given for 1, 2 or 4 weeks, in tinea capitis. Of 161 evaluable patients, 53 were treated with terbinafine for 1 week, 51 for 2 weeks and 57 for 4 weeks. Isolated pathogens included Trichophyton violaceum (71.5%), T. tonsurans (14.9%), T. verrucosum (4.3%), Microsporum audouinii (4.3%), M. canis (2.5%), T. schoenleinii (1.9%) and T. mentagrophytes (0.6%). The final evaluation, at 12 weeks, showed cure rates of 73.6, 80.4 and 85.9%, in the respective groups. The adverse effects noted, were not drug related. In our opinion, terbinafine given for 1, 2 or 4 weeks, is equally effective for most cases of tinea capitis.

Authors+Show Affiliations

Department of Dermatology, King Edward Medical College/Mayo Hospital, Lahore, Pakistan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial

Language

eng

PubMed ID

8776365

Citation

Haroon, T S., et al. "A Randomized Double-blind Comparative Study of Terbinafine for 1, 2 and 4 Weeks in Tinea Capitis." The British Journal of Dermatology, vol. 135, no. 1, 1996, pp. 86-8.
Haroon TS, Hussain I, Aman S, et al. A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. Br J Dermatol. 1996;135(1):86-8.
Haroon, T. S., Hussain, I., Aman, S., Jahangir, M., Kazmi, A. H., Sami, A. R., Nagi, A. H., Alvi, K. H., Iqbal, N., Khan, K. A., & Aziz, R. (1996). A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. The British Journal of Dermatology, 135(1), 86-8.
Haroon TS, et al. A Randomized Double-blind Comparative Study of Terbinafine for 1, 2 and 4 Weeks in Tinea Capitis. Br J Dermatol. 1996;135(1):86-8. PubMed PMID: 8776365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. AU - Haroon,T S, AU - Hussain,I, AU - Aman,S, AU - Jahangir,M, AU - Kazmi,A H, AU - Sami,A R, AU - Nagi,A H, AU - Alvi,K H, AU - Iqbal,N, AU - Khan,K A, AU - Aziz,R, PY - 1996/7/1/pubmed PY - 1996/7/1/medline PY - 1996/7/1/entrez SP - 86 EP - 8 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 135 IS - 1 N2 - We report a randomized, double-blind study, comparing the relative efficacy and tolerability of oral terbinafine, given for 1, 2 or 4 weeks, in tinea capitis. Of 161 evaluable patients, 53 were treated with terbinafine for 1 week, 51 for 2 weeks and 57 for 4 weeks. Isolated pathogens included Trichophyton violaceum (71.5%), T. tonsurans (14.9%), T. verrucosum (4.3%), Microsporum audouinii (4.3%), M. canis (2.5%), T. schoenleinii (1.9%) and T. mentagrophytes (0.6%). The final evaluation, at 12 weeks, showed cure rates of 73.6, 80.4 and 85.9%, in the respective groups. The adverse effects noted, were not drug related. In our opinion, terbinafine given for 1, 2 or 4 weeks, is equally effective for most cases of tinea capitis. SN - 0007-0963 UR - https://www.unboundmedicine.com/medline/citation/8776365/A_randomized_double_blind_comparative_study_of_terbinafine_for_1_2_and_4_weeks_in_tinea_capitis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=1996&volume=135&issue=1&spage=86 DB - PRIME DP - Unbound Medicine ER -