A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis.Br J Dermatol. 1996 Jul; 135(1):86-8.BJ
Abstract
We report a randomized, double-blind study, comparing the relative efficacy and tolerability of oral terbinafine, given for 1, 2 or 4 weeks, in tinea capitis. Of 161 evaluable patients, 53 were treated with terbinafine for 1 week, 51 for 2 weeks and 57 for 4 weeks. Isolated pathogens included Trichophyton violaceum (71.5%), T. tonsurans (14.9%), T. verrucosum (4.3%), Microsporum audouinii (4.3%), M. canis (2.5%), T. schoenleinii (1.9%) and T. mentagrophytes (0.6%). The final evaluation, at 12 weeks, showed cure rates of 73.6, 80.4 and 85.9%, in the respective groups. The adverse effects noted, were not drug related. In our opinion, terbinafine given for 1, 2 or 4 weeks, is equally effective for most cases of tinea capitis.
Links
MeSH
Pub Type(s)
Clinical Trial
Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial
Language
eng
PubMed ID
8776365
Citation
Haroon, T S., et al. "A Randomized Double-blind Comparative Study of Terbinafine for 1, 2 and 4 Weeks in Tinea Capitis." The British Journal of Dermatology, vol. 135, no. 1, 1996, pp. 86-8.
Haroon TS, Hussain I, Aman S, et al. A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. Br J Dermatol. 1996;135(1):86-8.
Haroon, T. S., Hussain, I., Aman, S., Jahangir, M., Kazmi, A. H., Sami, A. R., Nagi, A. H., Alvi, K. H., Iqbal, N., Khan, K. A., & Aziz, R. (1996). A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. The British Journal of Dermatology, 135(1), 86-8.
Haroon TS, et al. A Randomized Double-blind Comparative Study of Terbinafine for 1, 2 and 4 Weeks in Tinea Capitis. Br J Dermatol. 1996;135(1):86-8. PubMed PMID: 8776365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis.
AU - Haroon,T S,
AU - Hussain,I,
AU - Aman,S,
AU - Jahangir,M,
AU - Kazmi,A H,
AU - Sami,A R,
AU - Nagi,A H,
AU - Alvi,K H,
AU - Iqbal,N,
AU - Khan,K A,
AU - Aziz,R,
PY - 1996/7/1/pubmed
PY - 1996/7/1/medline
PY - 1996/7/1/entrez
SP - 86
EP - 8
JF - The British journal of dermatology
JO - Br J Dermatol
VL - 135
IS - 1
N2 - We report a randomized, double-blind study, comparing the relative efficacy and tolerability of oral terbinafine, given for 1, 2 or 4 weeks, in tinea capitis. Of 161 evaluable patients, 53 were treated with terbinafine for 1 week, 51 for 2 weeks and 57 for 4 weeks. Isolated pathogens included Trichophyton violaceum (71.5%), T. tonsurans (14.9%), T. verrucosum (4.3%), Microsporum audouinii (4.3%), M. canis (2.5%), T. schoenleinii (1.9%) and T. mentagrophytes (0.6%). The final evaluation, at 12 weeks, showed cure rates of 73.6, 80.4 and 85.9%, in the respective groups. The adverse effects noted, were not drug related. In our opinion, terbinafine given for 1, 2 or 4 weeks, is equally effective for most cases of tinea capitis.
SN - 0007-0963
UR - https://www.unboundmedicine.com/medline/citation/8776365/A_randomized_double_blind_comparative_study_of_terbinafine_for_1_2_and_4_weeks_in_tinea_capitis_
L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=1996&volume=135&issue=1&spage=86
DB - PRIME
DP - Unbound Medicine
ER -