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Detection of deep vein thrombosis with an automatic electrically calibrated strain gauge plethysmograph.
Surgery. 1977 Aug; 82(2):219-23.S

Abstract

A new strain gauge plethysmography was developed to permit accurate electrical calibration and automatic calculation of limb blood flow from a panel meter. This instrument was used to quantitate maximum venous outflow (MVO) in both limbs of 20 normal volunteers and 387 limbs of 195 patients with clinically suspected leg vein thrombosis. The MVO of normal subjects averaged 45 +/- 18 cc/minute/100 cc of calf tissue (mean +/- 1 SD). In 69 limbs with deep vein thrombosis documented by Doppler ultrasound and/or phlebography, the MVO averaged 17 +/- 13 cc/minute/100 cc, which was significantly less than that of normal limbs (p less than 0.001). Only three of 31 limbs with venous thrombosis above the knee had MVO above 20 cc/minute/100 cc, the lower limit of normal, for a diagnostic sensitivity of 90%. The specificity of a normal MVO in excluding deep vein thrombosis was 81%, with only a 1% rate of false-negative diagnoses above the knee. This automatic strain gauge plethysmograph has the attribute of providing rapid quantitation of limb venous hemodynamics which facilitates noninvasive diagnosis and follow-up assessment of venous disease.

Authors

Barnes RW
No affiliation info available
Hokanson DE
No affiliation info available
Wu KK
No affiliation info available
Hoak JC
No affiliation info available

MeSH

Doppler EffectFemoral VeinHumansIliac VeinLegPhlebographyPlethysmographyPopliteal VeinThrombophlebitisUltrasonography

Pub Type(s)

Journal Article

Language

eng

PubMed ID

877865

Citation

Barnes, R W., et al. "Detection of Deep Vein Thrombosis With an Automatic Electrically Calibrated Strain Gauge Plethysmograph." Surgery, vol. 82, no. 2, 1977, pp. 219-23.
Barnes RW, Hokanson DE, Wu KK, et al. Detection of deep vein thrombosis with an automatic electrically calibrated strain gauge plethysmograph. Surgery. 1977;82(2):219-23.
Barnes, R. W., Hokanson, D. E., Wu, K. K., & Hoak, J. C. (1977). Detection of deep vein thrombosis with an automatic electrically calibrated strain gauge plethysmograph. Surgery, 82(2), 219-23.
Barnes RW, et al. Detection of Deep Vein Thrombosis With an Automatic Electrically Calibrated Strain Gauge Plethysmograph. Surgery. 1977;82(2):219-23. PubMed PMID: 877865.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection of deep vein thrombosis with an automatic electrically calibrated strain gauge plethysmograph. AU - Barnes,R W, AU - Hokanson,D E, AU - Wu,K K, AU - Hoak,J C, PY - 1977/8/1/pubmed PY - 1977/8/1/medline PY - 1977/8/1/entrez SP - 219 EP - 23 JF - Surgery JO - Surgery VL - 82 IS - 2 N2 - A new strain gauge plethysmography was developed to permit accurate electrical calibration and automatic calculation of limb blood flow from a panel meter. This instrument was used to quantitate maximum venous outflow (MVO) in both limbs of 20 normal volunteers and 387 limbs of 195 patients with clinically suspected leg vein thrombosis. The MVO of normal subjects averaged 45 +/- 18 cc/minute/100 cc of calf tissue (mean +/- 1 SD). In 69 limbs with deep vein thrombosis documented by Doppler ultrasound and/or phlebography, the MVO averaged 17 +/- 13 cc/minute/100 cc, which was significantly less than that of normal limbs (p less than 0.001). Only three of 31 limbs with venous thrombosis above the knee had MVO above 20 cc/minute/100 cc, the lower limit of normal, for a diagnostic sensitivity of 90%. The specificity of a normal MVO in excluding deep vein thrombosis was 81%, with only a 1% rate of false-negative diagnoses above the knee. This automatic strain gauge plethysmograph has the attribute of providing rapid quantitation of limb venous hemodynamics which facilitates noninvasive diagnosis and follow-up assessment of venous disease. SN - 0039-6060 UR - https://www.unboundmedicine.com/medline/citation/877865/Detection_of_deep_vein_thrombosis_with_an_automatic_electrically_calibrated_strain_gauge_plethysmograph_ L2 - https://www.diseaseinfosearch.org/result/7087 DB - PRIME DP - Unbound Medicine ER -