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Evaluation of the risk of stone formation: study on crystalluria in patients with recurrent calcium oxalate urolithiasis.
Eur Urol. 1996; 29(4):456-61.EU

Abstract

OBJECTIVE

The aim of this study was to determine the usefulness of the morning calcium oxalate crystalluria in detecting stone formers particularly prone to recurrence.

METHODS

Over a 24-hour period of urine collection, the morning calcium oxalate crystalluria was evaluated as well as the risk of stone formation, established with Tiselius and Parks indices, for 25 recurrent stone formers (group 1) and 25 normal controls (group 2).

RESULTS

Morning crystalluria (type, size, number/ml and state of aggregate) and the Tiselius index were comparable in the two groups. Conversely, calciuria as well as the citrate/ calcium ratio and the Parks index varied significantly for stone formers and normal controls. No particular correlation appeared between crystalluria and indices of Tiselius and Parks, calciuria, calcium-oxalate product or calcium/ oxalate and citrate/calcium ratios.

CONCLUSIONS

Morning calcium oxalate crystalluria does not enable an efficient characterization of recurrent stone formers. Its discordance with others potential indicators of the risk of stone formation poses the problem of their respective validity and evokes the prevalence of still unknown inhibiting agents in the phenomenon of crystallization.

Authors+Show Affiliations

Department of Urology, Hôpital Lapeyronie, Montpellier, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8791054

Citation

Robert, M, et al. "Evaluation of the Risk of Stone Formation: Study On Crystalluria in Patients With Recurrent Calcium Oxalate Urolithiasis." European Urology, vol. 29, no. 4, 1996, pp. 456-61.
Robert M, Boularan AM, Delbos O, et al. Evaluation of the risk of stone formation: study on crystalluria in patients with recurrent calcium oxalate urolithiasis. Eur Urol. 1996;29(4):456-61.
Robert, M., Boularan, A. M., Delbos, O., Monnier, L., & Grasset, D. (1996). Evaluation of the risk of stone formation: study on crystalluria in patients with recurrent calcium oxalate urolithiasis. European Urology, 29(4), 456-61.
Robert M, et al. Evaluation of the Risk of Stone Formation: Study On Crystalluria in Patients With Recurrent Calcium Oxalate Urolithiasis. Eur Urol. 1996;29(4):456-61. PubMed PMID: 8791054.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the risk of stone formation: study on crystalluria in patients with recurrent calcium oxalate urolithiasis. AU - Robert,M, AU - Boularan,A M, AU - Delbos,O, AU - Monnier,L, AU - Grasset,D, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 456 EP - 61 JF - European urology JO - Eur Urol VL - 29 IS - 4 N2 - OBJECTIVE: The aim of this study was to determine the usefulness of the morning calcium oxalate crystalluria in detecting stone formers particularly prone to recurrence. METHODS: Over a 24-hour period of urine collection, the morning calcium oxalate crystalluria was evaluated as well as the risk of stone formation, established with Tiselius and Parks indices, for 25 recurrent stone formers (group 1) and 25 normal controls (group 2). RESULTS: Morning crystalluria (type, size, number/ml and state of aggregate) and the Tiselius index were comparable in the two groups. Conversely, calciuria as well as the citrate/ calcium ratio and the Parks index varied significantly for stone formers and normal controls. No particular correlation appeared between crystalluria and indices of Tiselius and Parks, calciuria, calcium-oxalate product or calcium/ oxalate and citrate/calcium ratios. CONCLUSIONS: Morning calcium oxalate crystalluria does not enable an efficient characterization of recurrent stone formers. Its discordance with others potential indicators of the risk of stone formation poses the problem of their respective validity and evokes the prevalence of still unknown inhibiting agents in the phenomenon of crystallization. SN - 0302-2838 UR - https://www.unboundmedicine.com/medline/citation/8791054/Evaluation_of_the_risk_of_stone_formation:_study_on_crystalluria_in_patients_with_recurrent_calcium_oxalate_urolithiasis_ DB - PRIME DP - Unbound Medicine ER -