The Jarisch-Herxheimer reaction in pregnancy: a nursing perspective.J Obstet Gynecol Neonatal Nurs. 1996 Jun; 25(5):383-6.JO
The Jarisch-Herxheimer reaction is a systemic event that can occur after the first dose of penicillin administration during treatment of syphilis. This article presents a case report of the Jarisch-Herxheimer reaction in a woman who was treated for syphilis at 27 weeks gestation. The proposed pathophysiology of the reaction is described, and complications of this reaction during pregnancy are reviewed. Recommendations for the nursing care of women treated for syphilis are provided.