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Crystal deposition disease. Diagnosis by electron microscopy.
Am J Med. 1977 Jul; 63(1):161-4.AJ

Abstract

The diagnosis of gout and pseudogout has traditionally been established by the identification, in synovial fluid, of monosodium urate and calcium pyrophosphate dihydrate crystals with compensated polarizing light microscopy. In this paper the utility of electron microscopy in establishing these diagnosis in two cases, when the conventional means of synovial fluid analysis had failed to do so, is discussed. The application of ultrastructural analysis of synovial fluid increases diagnostic capability in the crystal deposition diseases, and it is recommended for those patients in whom the more usual studies have not established a diagnosis.

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Publisher Full Text

Authors

Honig S
No affiliation info available
Gorevic P
No affiliation info available
Hoffstein S
No affiliation info available
Weissmann G
No affiliation info available

MeSH

AgedCalcium PyrophosphateChondrocalcinosisCrystallizationFemaleGoutHumansMaleMicroscopy, ElectronSynovial FluidUric Acid

Pub Type(s)

Case Reports
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

879190

Citation

Honig, S, et al. "Crystal Deposition Disease. Diagnosis By Electron Microscopy." The American Journal of Medicine, vol. 63, no. 1, 1977, pp. 161-4.
Honig S, Gorevic P, Hoffstein S, et al. Crystal deposition disease. Diagnosis by electron microscopy. Am J Med. 1977;63(1):161-4.
Honig, S., Gorevic, P., Hoffstein, S., & Weissmann, G. (1977). Crystal deposition disease. Diagnosis by electron microscopy. The American Journal of Medicine, 63(1), 161-4.
Honig S, et al. Crystal Deposition Disease. Diagnosis By Electron Microscopy. Am J Med. 1977;63(1):161-4. PubMed PMID: 879190.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Crystal deposition disease. Diagnosis by electron microscopy. AU - Honig,S, AU - Gorevic,P, AU - Hoffstein,S, AU - Weissmann,G, PY - 1977/7/1/pubmed PY - 1977/7/1/medline PY - 1977/7/1/entrez SP - 161 EP - 4 JF - The American journal of medicine JO - Am J Med VL - 63 IS - 1 N2 - The diagnosis of gout and pseudogout has traditionally been established by the identification, in synovial fluid, of monosodium urate and calcium pyrophosphate dihydrate crystals with compensated polarizing light microscopy. In this paper the utility of electron microscopy in establishing these diagnosis in two cases, when the conventional means of synovial fluid analysis had failed to do so, is discussed. The application of ultrastructural analysis of synovial fluid increases diagnostic capability in the crystal deposition diseases, and it is recommended for those patients in whom the more usual studies have not established a diagnosis. SN - 0002-9343 UR - https://www.unboundmedicine.com/medline/citation/879190/Crystal_deposition_disease__Diagnosis_by_electron_microscopy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9343(77)90128-0 DB - PRIME DP - Unbound Medicine ER -