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Serum and salivary antigliadin antibodies and serum IgA anti-endomysium antibodies as a screening test for coeliac disease.
Acta Paediatr 1996; 85(7):814-7AP

Abstract

Serum and salivary IgA and IgG antigliadin antibodies were determined by an enzyme-linked immunosorbent assay in 18 children with villous atrophy and 30 children on a gluten-free diet for coeliac disease in whom normal intestinal mucosa was found. Serum IgA anti-endomysium antibodies were also determined by an immunofluorescence method in these children. Serum IgG antigliadin and IgA anti-endomysium antibodies had the highest sensitivity (100 and 94.4%, respectively), followed by serum IgA antibodies to gliadin (72.2%), salivary IgA antigliadin (61.2%) and IgG antigliadin (50%) antibodies. The highest specificity was found for serum IgA anti-endomysium (100%) and IgA antigliadin (96.6%) antibodies and salivary IgA and IgG antigliadin antibodies (93.3%), while serum IgG antigliadin antibodies were found to be least specific (63.3%).

Authors+Show Affiliations

Department of Gastroenterology, Child Health Centre, Warsaw, Poland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8819547

Citation

Rujner, J, et al. "Serum and Salivary Antigliadin Antibodies and Serum IgA Anti-endomysium Antibodies as a Screening Test for Coeliac Disease." Acta Paediatrica (Oslo, Norway : 1992), vol. 85, no. 7, 1996, pp. 814-7.
Rujner J, Socha J, Barra E, et al. Serum and salivary antigliadin antibodies and serum IgA anti-endomysium antibodies as a screening test for coeliac disease. Acta Paediatr. 1996;85(7):814-7.
Rujner, J., Socha, J., Barra, E., Gregorek, H., Madaliński, K., Woźniewicz, B., & Giera, B. (1996). Serum and salivary antigliadin antibodies and serum IgA anti-endomysium antibodies as a screening test for coeliac disease. Acta Paediatrica (Oslo, Norway : 1992), 85(7), pp. 814-7.
Rujner J, et al. Serum and Salivary Antigliadin Antibodies and Serum IgA Anti-endomysium Antibodies as a Screening Test for Coeliac Disease. Acta Paediatr. 1996;85(7):814-7. PubMed PMID: 8819547.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum and salivary antigliadin antibodies and serum IgA anti-endomysium antibodies as a screening test for coeliac disease. AU - Rujner,J, AU - Socha,J, AU - Barra,E, AU - Gregorek,H, AU - Madaliński,K, AU - Woźniewicz,B, AU - Giera,B, PY - 1996/7/1/pubmed PY - 1996/7/1/medline PY - 1996/7/1/entrez SP - 814 EP - 7 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 85 IS - 7 N2 - Serum and salivary IgA and IgG antigliadin antibodies were determined by an enzyme-linked immunosorbent assay in 18 children with villous atrophy and 30 children on a gluten-free diet for coeliac disease in whom normal intestinal mucosa was found. Serum IgA anti-endomysium antibodies were also determined by an immunofluorescence method in these children. Serum IgG antigliadin and IgA anti-endomysium antibodies had the highest sensitivity (100 and 94.4%, respectively), followed by serum IgA antibodies to gliadin (72.2%), salivary IgA antigliadin (61.2%) and IgG antigliadin (50%) antibodies. The highest specificity was found for serum IgA anti-endomysium (100%) and IgA antigliadin (96.6%) antibodies and salivary IgA and IgG antigliadin antibodies (93.3%), while serum IgG antigliadin antibodies were found to be least specific (63.3%). SN - 0803-5253 UR - https://www.unboundmedicine.com/medline/citation/8819547/Serum_and_salivary_antigliadin_antibodies_and_serum_IgA_anti_endomysium_antibodies_as_a_screening_test_for_coeliac_disease_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0803-5253&date=1996&volume=85&issue=7&spage=814 DB - PRIME DP - Unbound Medicine ER -