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Clinically occult lung cancer with positive sputum cytology and primarily negative radiological findings.
Scand J Respir Dis. 1977 Jun; 58(3):134-44.SJ

Abstract

Five patients with early clinically occult squamous cell carcinoma of the bronchus were reviewed with respect to previous sputum cytological examinations and clinical investigations. In one patient, selective bronchial washings demonstrated the site of the tumour and the patient was successfully operated. In the remaining four patients the interval between cytological diagnosis and radiological, bronchoscopical and/or histological demonstration of the tumour varied between 2 months and 9 years. It seems possible that the duration of bronchogenic carcinoma in situ may be of similar magnitude as that of carcinoma in situ of the cervix (10-15 years). The considerably higher frequency of early stromal invasion after semi-serial sectioning of carcinoma in situ of the bronchus compared with carcinoma in situ of the cervix is emphasized. The results stress that a diagnostic delay of several years is not acceptable, as the possibility of successful treatment will be greatly diminished in such cases.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

882852

Citation

Nasiell, M, et al. "Clinically Occult Lung Cancer With Positive Sputum Cytology and Primarily Negative Radiological Findings." Scandinavian Journal of Respiratory Diseases, vol. 58, no. 3, 1977, pp. 134-44.
Nasiell M, Sinner W, Tornvall G, et al. Clinically occult lung cancer with positive sputum cytology and primarily negative radiological findings. Scand J Respir Dis. 1977;58(3):134-44.
Nasiell, M., Sinner, W., Tornvall, G., Roger, V., Vogel, B., & Enstad, I. (1977). Clinically occult lung cancer with positive sputum cytology and primarily negative radiological findings. Scandinavian Journal of Respiratory Diseases, 58(3), 134-44.
Nasiell M, et al. Clinically Occult Lung Cancer With Positive Sputum Cytology and Primarily Negative Radiological Findings. Scand J Respir Dis. 1977;58(3):134-44. PubMed PMID: 882852.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinically occult lung cancer with positive sputum cytology and primarily negative radiological findings. AU - Nasiell,M, AU - Sinner,W, AU - Tornvall,G, AU - Roger,V, AU - Vogel,B, AU - Enstad,I, PY - 1977/6/1/pubmed PY - 1977/6/1/medline PY - 1977/6/1/entrez SP - 134 EP - 44 JF - Scandinavian journal of respiratory diseases JO - Scand J Respir Dis VL - 58 IS - 3 N2 - Five patients with early clinically occult squamous cell carcinoma of the bronchus were reviewed with respect to previous sputum cytological examinations and clinical investigations. In one patient, selective bronchial washings demonstrated the site of the tumour and the patient was successfully operated. In the remaining four patients the interval between cytological diagnosis and radiological, bronchoscopical and/or histological demonstration of the tumour varied between 2 months and 9 years. It seems possible that the duration of bronchogenic carcinoma in situ may be of similar magnitude as that of carcinoma in situ of the cervix (10-15 years). The considerably higher frequency of early stromal invasion after semi-serial sectioning of carcinoma in situ of the bronchus compared with carcinoma in situ of the cervix is emphasized. The results stress that a diagnostic delay of several years is not acceptable, as the possibility of successful treatment will be greatly diminished in such cases. SN - 0036-5572 UR - https://www.unboundmedicine.com/medline/citation/882852/Clinically_occult_lung_cancer_with_positive_sputum_cytology_and_primarily_negative_radiological_findings_ L2 - http://www.diseaseinfosearch.org/result/4334 DB - PRIME DP - Unbound Medicine ER -