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Ofuji's disease and cytokines: Remission of eosinophilic pustular folliculitis associated with increased serum concentrations of interferon gamma.
Dermatology. 1996; 192(1):16-8.D

Abstract

BACKGROUND AND OBJECTIVE

Eosinophilic pustular folliculitis (EPF) is a distinct inflammatory dermatosis of unknown etiology. The aim of this study is to evaluate the serum levels of cytokines in 3 patients with EPF before and after treatment with indomethacin.

RESULTS

Serum levels of interleukin 4 (IL-4) were elevated in patients with EPF. The remission of EPF was associated with increased serum concentrations of interferon gamma with no essential change of serum levels of IL-4.

CONCLUSION

These results suggest that subtle changes in serum levels of cytokines are involved in the remission of EPF and that indomethacin may provide the remission of EPF by altering cytokine production in patients with EPF.

Authors+Show Affiliations

Department of Dermatology, Kyorin University School of Medicine, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8832945

Citation

Teraki, Y, et al. "Ofuji's Disease and Cytokines: Remission of Eosinophilic Pustular Folliculitis Associated With Increased Serum Concentrations of Interferon Gamma." Dermatology (Basel, Switzerland), vol. 192, no. 1, 1996, pp. 16-8.
Teraki Y, Imanishi K, Shiohara T. Ofuji's disease and cytokines: Remission of eosinophilic pustular folliculitis associated with increased serum concentrations of interferon gamma. Dermatology (Basel). 1996;192(1):16-8.
Teraki, Y., Imanishi, K., & Shiohara, T. (1996). Ofuji's disease and cytokines: Remission of eosinophilic pustular folliculitis associated with increased serum concentrations of interferon gamma. Dermatology (Basel, Switzerland), 192(1), 16-8.
Teraki Y, Imanishi K, Shiohara T. Ofuji's Disease and Cytokines: Remission of Eosinophilic Pustular Folliculitis Associated With Increased Serum Concentrations of Interferon Gamma. Dermatology (Basel). 1996;192(1):16-8. PubMed PMID: 8832945.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ofuji's disease and cytokines: Remission of eosinophilic pustular folliculitis associated with increased serum concentrations of interferon gamma. AU - Teraki,Y, AU - Imanishi,K, AU - Shiohara,T, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 16 EP - 8 JF - Dermatology (Basel, Switzerland) JO - Dermatology (Basel) VL - 192 IS - 1 N2 - BACKGROUND AND OBJECTIVE: Eosinophilic pustular folliculitis (EPF) is a distinct inflammatory dermatosis of unknown etiology. The aim of this study is to evaluate the serum levels of cytokines in 3 patients with EPF before and after treatment with indomethacin. RESULTS: Serum levels of interleukin 4 (IL-4) were elevated in patients with EPF. The remission of EPF was associated with increased serum concentrations of interferon gamma with no essential change of serum levels of IL-4. CONCLUSION: These results suggest that subtle changes in serum levels of cytokines are involved in the remission of EPF and that indomethacin may provide the remission of EPF by altering cytokine production in patients with EPF. SN - 1018-8665 UR - https://www.unboundmedicine.com/medline/citation/8832945/Ofuji's_disease_and_cytokines:_Remission_of_eosinophilic_pustular_folliculitis_associated_with_increased_serum_concentrations_of_interferon_gamma_ L2 - https://www.karger.com?DOI=10.1159/000246306 DB - PRIME DP - Unbound Medicine ER -