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Pregnancy following thyroid hormone treatment in a patient with amenorrhea-galactorrhea due to primary hypothyroidism.
Fertil Steril. 1977 Aug; 28(8):878-80.FS

Abstract

A 32-year-old female with amenorrhea-galactorrhea due to primary hypothyroidism was treated with thyroid hormones, and serum levels of thyrotropin (TSH), prolactin (PRL), triiodothyronine (T3), thyroxin (T4), and T3 resin sponge uptake (RT3U) were measured throughout the course of treatment. The elevated serum levels of TSH and PRL fell into the normal range following T3 treatment. Subsequently, the menstrual cycle was restored within 1 month, and galactorrhea completely ceased and conception was achieved within 3 months. Desiccated thyroid was administered during pregnancy, and the patient gave birth to a female infant. Impaired secretion of PRL during pregnancy and poor milk secretion with blunted response of PRL to the suckling stimulus during the puerperium were noted.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

885277

Citation

Aono, T, et al. "Pregnancy Following Thyroid Hormone Treatment in a Patient With Amenorrhea-galactorrhea Due to Primary Hypothyroidism." Fertility and Sterility, vol. 28, no. 8, 1977, pp. 878-80.
Aono T, Shioji T, Onishi T, et al. Pregnancy following thyroid hormone treatment in a patient with amenorrhea-galactorrhea due to primary hypothyroidism. Fertil Steril. 1977;28(8):878-80.
Aono, T., Shioji, T., Onishi, T., Kurachi, H., & Miyai, K. (1977). Pregnancy following thyroid hormone treatment in a patient with amenorrhea-galactorrhea due to primary hypothyroidism. Fertility and Sterility, 28(8), 878-80.
Aono T, et al. Pregnancy Following Thyroid Hormone Treatment in a Patient With Amenorrhea-galactorrhea Due to Primary Hypothyroidism. Fertil Steril. 1977;28(8):878-80. PubMed PMID: 885277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pregnancy following thyroid hormone treatment in a patient with amenorrhea-galactorrhea due to primary hypothyroidism. AU - Aono,T, AU - Shioji,T, AU - Onishi,T, AU - Kurachi,H, AU - Miyai,K, PY - 1977/8/1/pubmed PY - 1977/8/1/medline PY - 1977/8/1/entrez KW - Amenorrhea KW - Biology KW - Case Studies KW - Central Nervous System Effects KW - Diseases KW - Endocrine System KW - Galactorrhea KW - Hormones--side effects KW - Hormones--therapeutic use KW - Lactation KW - Maternal Physiology KW - Menstruation Disorders KW - Physiology KW - Pituitary Hormones KW - Prolactin--analysis KW - Puerperal Disorders KW - Research Methodology KW - Studies SP - 878 EP - 80 JF - Fertility and sterility JO - Fertil Steril VL - 28 IS - 8 N2 - A 32-year-old female with amenorrhea-galactorrhea due to primary hypothyroidism was treated with thyroid hormones, and serum levels of thyrotropin (TSH), prolactin (PRL), triiodothyronine (T3), thyroxin (T4), and T3 resin sponge uptake (RT3U) were measured throughout the course of treatment. The elevated serum levels of TSH and PRL fell into the normal range following T3 treatment. Subsequently, the menstrual cycle was restored within 1 month, and galactorrhea completely ceased and conception was achieved within 3 months. Desiccated thyroid was administered during pregnancy, and the patient gave birth to a female infant. Impaired secretion of PRL during pregnancy and poor milk secretion with blunted response of PRL to the suckling stimulus during the puerperium were noted. SN - 0015-0282 UR - https://www.unboundmedicine.com/medline/citation/885277/Pregnancy_following_thyroid_hormone_treatment_in_a_patient_with_amenorrhea_galactorrhea_due_to_primary_hypothyroidism_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(16)42745-7 DB - PRIME DP - Unbound Medicine ER -