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Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar).
Prostaglandins Leukot Essent Fatty Acids. 1996 Mar; 54(3):173-82.PL

Abstract

Atlantic salmon (Salmo salar) post-smolts were fed diets containing either Fosol (FO), a North Sea fish oil, sunflower oil (SO), linseed oil (LO) or Marinol K (MO), a southern hemisphere fish oil rich in 20:5(n-3) for 12 weeks. A macrophage-enriched leucocyte preparation was obtained from head kidney and the fatty acid compositions of the individual membrane phospholipids measured. In general phospholipids from SO- and LO-fed fish had increased 18:2(n-6), 20:2(n-6) and 20:3(n-6) compared to the fish oil treatments while LO-fed fish had lower 20:4(n-6) than any other dietary treatment. Fish fed LO also had increased 18:3(n-3), 18:4(n-3), 20:3(n-3) and 20:4(n-3). The 20:5(n-3) content of kidney macrophage-enriched leucocyte phospholipids was highest in MO-fed fish followed by FO- and LO-fed fish with the lowest level in fish fed SO. The overall effect on the ratio of eicosanoid precursors, 20:4/20:5, showed the highest value in SO-fed fish and the lowest in fish fed LO. Production of LTB5 by kidney macrophage-enriched leucocytes stimulated with A23187 was highest in MO-fed fish and lowest in those fed SO. Production of LTB4 was greatest in SO-fed fish and lowest in fish fed LO. Serum Ig levels were significantly affected by dietary treatment with highest values in fish fed FO and SO and lowest in fish fed MO and LO.

Authors+Show Affiliations

N.E.R.C. Unit of Aquatic Biochemistry, School of Natural Sciences, University of Stirling, Stirling, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8860104

Citation

Bell, J G., et al. "Dietary Lipid Affects Phospholipid Fatty Acid Compositions, Eicosanoid Production and Immune Function in Atlantic Salmon (Salmo Salar)." Prostaglandins, Leukotrienes, and Essential Fatty Acids, vol. 54, no. 3, 1996, pp. 173-82.
Bell JG, Ashton I, Secombes CJ, et al. Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar). Prostaglandins Leukot Essent Fatty Acids. 1996;54(3):173-82.
Bell, J. G., Ashton, I., Secombes, C. J., Weitzel, B. R., Dick, J. R., & Sargent, J. R. (1996). Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar). Prostaglandins, Leukotrienes, and Essential Fatty Acids, 54(3), 173-82.
Bell JG, et al. Dietary Lipid Affects Phospholipid Fatty Acid Compositions, Eicosanoid Production and Immune Function in Atlantic Salmon (Salmo Salar). Prostaglandins Leukot Essent Fatty Acids. 1996;54(3):173-82. PubMed PMID: 8860104.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar). AU - Bell,J G, AU - Ashton,I, AU - Secombes,C J, AU - Weitzel,B R, AU - Dick,J R, AU - Sargent,J R, PY - 1996/3/1/pubmed PY - 1996/3/1/medline PY - 1996/3/1/entrez SP - 173 EP - 82 JF - Prostaglandins, leukotrienes, and essential fatty acids JO - Prostaglandins Leukot. Essent. Fatty Acids VL - 54 IS - 3 N2 - Atlantic salmon (Salmo salar) post-smolts were fed diets containing either Fosol (FO), a North Sea fish oil, sunflower oil (SO), linseed oil (LO) or Marinol K (MO), a southern hemisphere fish oil rich in 20:5(n-3) for 12 weeks. A macrophage-enriched leucocyte preparation was obtained from head kidney and the fatty acid compositions of the individual membrane phospholipids measured. In general phospholipids from SO- and LO-fed fish had increased 18:2(n-6), 20:2(n-6) and 20:3(n-6) compared to the fish oil treatments while LO-fed fish had lower 20:4(n-6) than any other dietary treatment. Fish fed LO also had increased 18:3(n-3), 18:4(n-3), 20:3(n-3) and 20:4(n-3). The 20:5(n-3) content of kidney macrophage-enriched leucocyte phospholipids was highest in MO-fed fish followed by FO- and LO-fed fish with the lowest level in fish fed SO. The overall effect on the ratio of eicosanoid precursors, 20:4/20:5, showed the highest value in SO-fed fish and the lowest in fish fed LO. Production of LTB5 by kidney macrophage-enriched leucocytes stimulated with A23187 was highest in MO-fed fish and lowest in those fed SO. Production of LTB4 was greatest in SO-fed fish and lowest in fish fed LO. Serum Ig levels were significantly affected by dietary treatment with highest values in fish fed FO and SO and lowest in fish fed MO and LO. SN - 0952-3278 UR - https://www.unboundmedicine.com/medline/citation/8860104/Dietary_lipid_affects_phospholipid_fatty_acid_compositions_eicosanoid_production_and_immune_function_in_Atlantic_salmon__Salmo_salar__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0952-3278(96)90013-7 DB - PRIME DP - Unbound Medicine ER -