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Xanthones from Hypericum roeperanum.
Phytochemistry. 1996 Sep; 43(2):513-20.P

Abstract

Four new xanthones have been isolated from the roots of Hypericum roeperanum. Their structures have been established by a combination of spectroscopic and chemical methods as 1,6-dihydroxy-5-methoxy-4',5'-dihydro-4',4',5'-trimethylfurano- (2',3':3,4)-xanthone (5-O-methyl-2-deprenylrheediaxanthone B), 1,6-dihydroxy-5-methoxy-6',6'-dimethylpyrano-(2',3':3,4)-xanthone (5-O-methylisojacareubin), 1,3,5,6-tetrahydroxy-2-(2',2'-dimethyl-4'-isopropenyl)-cyclopen tanylxanthone (5-O-demethylpaxanthonin) and 1,3,5,6-tetrahydroxy-4-trans-sesquilavandulylxanthone (roeperanone). In addition, 2-hydroxyxanthone, 5-hydroxy-2-methoxyxanthone, 1,5-dihydroxy-2-methoxyxanthone, 2-deprenyl rheediaxanthone B, isojacareubin and calycinoxanthone D have been isolated and characterized. Some of the isolated xanthones exhibited antifungal activity against Candida albicans.

Authors+Show Affiliations

Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8862040

Citation

Rath, G, et al. "Xanthones From Hypericum Roeperanum." Phytochemistry, vol. 43, no. 2, 1996, pp. 513-20.
Rath G, Potterat O, Mavi S, et al. Xanthones from Hypericum roeperanum. Phytochemistry. 1996;43(2):513-20.
Rath, G., Potterat, O., Mavi, S., & Hostettmann, K. (1996). Xanthones from Hypericum roeperanum. Phytochemistry, 43(2), 513-20.
Rath G, et al. Xanthones From Hypericum Roeperanum. Phytochemistry. 1996;43(2):513-20. PubMed PMID: 8862040.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Xanthones from Hypericum roeperanum. AU - Rath,G, AU - Potterat,O, AU - Mavi,S, AU - Hostettmann,K, PY - 1996/9/1/pubmed PY - 1996/9/1/medline PY - 1996/9/1/entrez SP - 513 EP - 20 JF - Phytochemistry JO - Phytochemistry VL - 43 IS - 2 N2 - Four new xanthones have been isolated from the roots of Hypericum roeperanum. Their structures have been established by a combination of spectroscopic and chemical methods as 1,6-dihydroxy-5-methoxy-4',5'-dihydro-4',4',5'-trimethylfurano- (2',3':3,4)-xanthone (5-O-methyl-2-deprenylrheediaxanthone B), 1,6-dihydroxy-5-methoxy-6',6'-dimethylpyrano-(2',3':3,4)-xanthone (5-O-methylisojacareubin), 1,3,5,6-tetrahydroxy-2-(2',2'-dimethyl-4'-isopropenyl)-cyclopen tanylxanthone (5-O-demethylpaxanthonin) and 1,3,5,6-tetrahydroxy-4-trans-sesquilavandulylxanthone (roeperanone). In addition, 2-hydroxyxanthone, 5-hydroxy-2-methoxyxanthone, 1,5-dihydroxy-2-methoxyxanthone, 2-deprenyl rheediaxanthone B, isojacareubin and calycinoxanthone D have been isolated and characterized. Some of the isolated xanthones exhibited antifungal activity against Candida albicans. SN - 0031-9422 UR - https://www.unboundmedicine.com/medline/citation/8862040/Xanthones_from_Hypericum_roeperanum_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0031942296002841 DB - PRIME DP - Unbound Medicine ER -