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Perinatal outcome after embryo transfer in ovum recipients. A comparison with standard in vitro fertilization.
J Reprod Med. 1996 Sep; 41(9):640-4.JR

Abstract

OBJECTIVE

To compare perinatal outcome after embryo transfer vs. standard in vitro fertilization (IVF) in ovum recipients.

STUDY DESIGN

We reviewed 22 consecutive ovum donor pregnancies delivered at Mount Sinai Hospital between July 1989 and November 1992 and matched them for age, parity and order of gestation to a control group who underwent standard IVF-embryo transfer (ET) during that period.

RESULTS

The two groups showed similar rates of maternal complications, including hypertensive disorders, gestational diabetes and puerperal complications. When compared to patients undergoing autologous IVF-ET, ovum recipients had a lower rate of preterm labor (22.7% vs. 54.6%, P < .05), a higher mean gestational age at delivery (38.7 vs. 36.1 weeks, P < .01) and increased mean birth weight of neonates (2,924 vs. 2,374 g, P < .005). Though infants born through traditional IVF-ET were more likely to be preterm, Apgar scores were similar at one and five minutes. Our data support the generally favorable outcome seen in pregnancies conceived through ovum donation despite the fact that many of these patients had prior poor prenatal outcomes, long intervals until conception, and coexisting medical conditions.

CONCLUSION

Ovum donation in women of comparable ages has obstetric outcomes equal to or better than patients undergoing traditional IVF-ET. Obstetric and perinatal outcome do not seem to be impaired in patients receiving donated oocytes.

Authors+Show Affiliations

Department of Obstetrics, Gynecology and Reproductive Sciences, Mount Sinai School of Medicine, New York, New York, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8887187

Citation

Friedman, F, et al. "Perinatal Outcome After Embryo Transfer in Ovum Recipients. a Comparison With Standard in Vitro Fertilization." The Journal of Reproductive Medicine, vol. 41, no. 9, 1996, pp. 640-4.
Friedman F, Copperman AB, Brodman ML, et al. Perinatal outcome after embryo transfer in ovum recipients. A comparison with standard in vitro fertilization. J Reprod Med. 1996;41(9):640-4.
Friedman, F., Copperman, A. B., Brodman, M. L., Shah, D., Sandler, B., & Grunfeld, L. (1996). Perinatal outcome after embryo transfer in ovum recipients. A comparison with standard in vitro fertilization. The Journal of Reproductive Medicine, 41(9), 640-4.
Friedman F, et al. Perinatal Outcome After Embryo Transfer in Ovum Recipients. a Comparison With Standard in Vitro Fertilization. J Reprod Med. 1996;41(9):640-4. PubMed PMID: 8887187.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Perinatal outcome after embryo transfer in ovum recipients. A comparison with standard in vitro fertilization. AU - Friedman,F,Jr AU - Copperman,A B, AU - Brodman,M L, AU - Shah,D, AU - Sandler,B, AU - Grunfeld,L, PY - 1996/9/1/pubmed PY - 2001/3/28/medline PY - 1996/9/1/entrez SP - 640 EP - 4 JF - The Journal of reproductive medicine JO - J Reprod Med VL - 41 IS - 9 N2 - OBJECTIVE: To compare perinatal outcome after embryo transfer vs. standard in vitro fertilization (IVF) in ovum recipients. STUDY DESIGN: We reviewed 22 consecutive ovum donor pregnancies delivered at Mount Sinai Hospital between July 1989 and November 1992 and matched them for age, parity and order of gestation to a control group who underwent standard IVF-embryo transfer (ET) during that period. RESULTS: The two groups showed similar rates of maternal complications, including hypertensive disorders, gestational diabetes and puerperal complications. When compared to patients undergoing autologous IVF-ET, ovum recipients had a lower rate of preterm labor (22.7% vs. 54.6%, P < .05), a higher mean gestational age at delivery (38.7 vs. 36.1 weeks, P < .01) and increased mean birth weight of neonates (2,924 vs. 2,374 g, P < .005). Though infants born through traditional IVF-ET were more likely to be preterm, Apgar scores were similar at one and five minutes. Our data support the generally favorable outcome seen in pregnancies conceived through ovum donation despite the fact that many of these patients had prior poor prenatal outcomes, long intervals until conception, and coexisting medical conditions. CONCLUSION: Ovum donation in women of comparable ages has obstetric outcomes equal to or better than patients undergoing traditional IVF-ET. Obstetric and perinatal outcome do not seem to be impaired in patients receiving donated oocytes. SN - 0024-7758 UR - https://www.unboundmedicine.com/medline/citation/8887187/Perinatal_outcome_after_embryo_transfer_in_ovum_recipients__A_comparison_with_standard_in_vitro_fertilization_ DB - PRIME DP - Unbound Medicine ER -