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Results of large penetrating keratoplasty in microbial keratitis.
Cornea 1996; 15(6):571-6C

Abstract

Extensive corneal disease secondary to microbial keratitis can result in frank or impending corneal perforation requiring a large penetrating keratoplasty. In an 8-year period, 26 penetrating keratoplasties with recipient beds of > or = 9.5 mm were performed on 22 eyes: 11 for bacterial keratitis, 10 for fungal keratitis, and one for a mixed bacterial and fungal keratitis. The graft failed in 18 of 19 eyes (94.7%), with a median time to failure of 12.9 weeks in bacterial keratitis and 4.0 weeks in fungal keratitis. After large keratoplasty, 17 of 20 eyes (85.0%) maintained the structural integrity of the globe. The remainder became phthisical or required enucleation. With preservation of the structural integrity of the globe, a subsequent smaller optical penetrating keratoplasty is an option in some of these eyes.

Authors+Show Affiliations

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8899268

Citation

Cristol, S M., et al. "Results of Large Penetrating Keratoplasty in Microbial Keratitis." Cornea, vol. 15, no. 6, 1996, pp. 571-6.
Cristol SM, Alfonso EC, Guildford JH, et al. Results of large penetrating keratoplasty in microbial keratitis. Cornea. 1996;15(6):571-6.
Cristol, S. M., Alfonso, E. C., Guildford, J. H., Roussel, T. J., & Culbertson, W. W. (1996). Results of large penetrating keratoplasty in microbial keratitis. Cornea, 15(6), pp. 571-6.
Cristol SM, et al. Results of Large Penetrating Keratoplasty in Microbial Keratitis. Cornea. 1996;15(6):571-6. PubMed PMID: 8899268.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Results of large penetrating keratoplasty in microbial keratitis. AU - Cristol,S M, AU - Alfonso,E C, AU - Guildford,J H, AU - Roussel,T J, AU - Culbertson,W W, PY - 1996/11/1/pubmed PY - 1996/11/1/medline PY - 1996/11/1/entrez SP - 571 EP - 6 JF - Cornea JO - Cornea VL - 15 IS - 6 N2 - Extensive corneal disease secondary to microbial keratitis can result in frank or impending corneal perforation requiring a large penetrating keratoplasty. In an 8-year period, 26 penetrating keratoplasties with recipient beds of > or = 9.5 mm were performed on 22 eyes: 11 for bacterial keratitis, 10 for fungal keratitis, and one for a mixed bacterial and fungal keratitis. The graft failed in 18 of 19 eyes (94.7%), with a median time to failure of 12.9 weeks in bacterial keratitis and 4.0 weeks in fungal keratitis. After large keratoplasty, 17 of 20 eyes (85.0%) maintained the structural integrity of the globe. The remainder became phthisical or required enucleation. With preservation of the structural integrity of the globe, a subsequent smaller optical penetrating keratoplasty is an option in some of these eyes. SN - 0277-3740 UR - https://www.unboundmedicine.com/medline/citation/8899268/Results_of_large_penetrating_keratoplasty_in_microbial_keratitis_ L2 - http://Insights.ovid.com/pubmed?pmid=8899268 DB - PRIME DP - Unbound Medicine ER -