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Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet.
Am J Clin Nutr 1996; 64(6):935-43AJ

Abstract

Current dietary recommendation for cardiovascular disease risk reduction and recommended dietary allowances (RDAs) were used to develop a nutritionally complete prepackaged prepared meal plan specifically designed to reduce the risk of cardiovascular disease. In the current study we tested patient acceptance of the diet as defined by measures of quality of life. In a randomized, parallel-design, multicenter clinical trial, 77 persons with hypertension, diabetes mellitus, dyslipidemia, or a combination of two or more of these conditions were recruited and randomly assigned to either a prepared meal plan (n = 39) or a comparable self-selected diet (n = 38) for 10 wk. The prepared meal plan met both the RDAs for all essential micronutrients and the dietary recommendations of national health organizations for macronutrients, cholesterol, sodium, and fiber. The prescribed self-selected diet was matched for macronutrients. Quality of life, as measured by a battery of instruments, was the major endpoint. Individuals consuming the prepared meal plan had significant improvements in mental health (P < 0.01), general perceived health (P < 0.005), daily activities (P < 0.05), work performance (P < 0.005), affect (P < 0.01), and nutritional health perceptions (P < 0.001), and reductions in nutrition hassles based on a standardized questionnaire (P < 0.001). The self-selected-diet group had significant improvements in nutritional health perceptions (P < 0.001) and affect (P < 0.001). There were significant improvements in weight (P < 0.001), blood pressure (P < 0.001), cholesterol (P < 0.002), low-density lipoproteins (P < 0.001), glucose (P < 0.014), and glycated hemoglobin (Hb A(1c) (P < 0.004) that were comparable in both groups. In summary, this study shows that a nutritionally complete diet, whether prepackaged or self-selected, improves multiple risk factors for cardiovascular disease. The prepackaged prepared meal plan had the added benefit of a greater improvement in quality of life.

Authors+Show Affiliations

McMaster University, Health Sciences Centre, Hamilton, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8942420

Citation

Hatton, D C., et al. "Improved Quality of Life in Patients With Generalized Cardiovascular Metabolic Disease On a Prepared Diet." The American Journal of Clinical Nutrition, vol. 64, no. 6, 1996, pp. 935-43.
Hatton DC, Haynes RB, Oparil S, et al. Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet. Am J Clin Nutr. 1996;64(6):935-43.
Hatton, D. C., Haynes, R. B., Oparil, S., Kris-Etherton, P., Pi-Sunyer, F. X., Resnick, L. M., ... McCarron, D. A. (1996). Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet. The American Journal of Clinical Nutrition, 64(6), pp. 935-43.
Hatton DC, et al. Improved Quality of Life in Patients With Generalized Cardiovascular Metabolic Disease On a Prepared Diet. Am J Clin Nutr. 1996;64(6):935-43. PubMed PMID: 8942420.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet. AU - Hatton,D C, AU - Haynes,R B, AU - Oparil,S, AU - Kris-Etherton,P, AU - Pi-Sunyer,F X, AU - Resnick,L M, AU - Stern,J S, AU - Clark,S, AU - McMahon,M, AU - Morris,C, AU - Metz,J, AU - Ward,A, AU - Holcomb,S, AU - McCarron,D A, PY - 1996/12/1/pubmed PY - 1996/12/1/medline PY - 1996/12/1/entrez SP - 935 EP - 43 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 64 IS - 6 N2 - Current dietary recommendation for cardiovascular disease risk reduction and recommended dietary allowances (RDAs) were used to develop a nutritionally complete prepackaged prepared meal plan specifically designed to reduce the risk of cardiovascular disease. In the current study we tested patient acceptance of the diet as defined by measures of quality of life. In a randomized, parallel-design, multicenter clinical trial, 77 persons with hypertension, diabetes mellitus, dyslipidemia, or a combination of two or more of these conditions were recruited and randomly assigned to either a prepared meal plan (n = 39) or a comparable self-selected diet (n = 38) for 10 wk. The prepared meal plan met both the RDAs for all essential micronutrients and the dietary recommendations of national health organizations for macronutrients, cholesterol, sodium, and fiber. The prescribed self-selected diet was matched for macronutrients. Quality of life, as measured by a battery of instruments, was the major endpoint. Individuals consuming the prepared meal plan had significant improvements in mental health (P < 0.01), general perceived health (P < 0.005), daily activities (P < 0.05), work performance (P < 0.005), affect (P < 0.01), and nutritional health perceptions (P < 0.001), and reductions in nutrition hassles based on a standardized questionnaire (P < 0.001). The self-selected-diet group had significant improvements in nutritional health perceptions (P < 0.001) and affect (P < 0.001). There were significant improvements in weight (P < 0.001), blood pressure (P < 0.001), cholesterol (P < 0.002), low-density lipoproteins (P < 0.001), glucose (P < 0.014), and glycated hemoglobin (Hb A(1c) (P < 0.004) that were comparable in both groups. In summary, this study shows that a nutritionally complete diet, whether prepackaged or self-selected, improves multiple risk factors for cardiovascular disease. The prepackaged prepared meal plan had the added benefit of a greater improvement in quality of life. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/8942420/Improved_quality_of_life_in_patients_with_generalized_cardiovascular_metabolic_disease_on_a_prepared_diet_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/64.6.935 DB - PRIME DP - Unbound Medicine ER -