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Alcohol, thiamin deficiency, and neuropsychological disorders.
Alcohol Alcohol Suppl. 1994; 2:267-72.AA

Abstract

In this paper, two of the major themes in contemporary neuropsychological research are reviewed. These are the nature of cognitive impairment observed in alcohol related brain injury, and the cause or causes of alcohol related brain injury. Two experiments are briefly reported which address these issues. The first experiment concerns the nature of abilities which are involved in a test of memory (delayed matching to sample), which is fundamental to current experimental models of human amnesia. The second experiment involves preliminary data from a randomised, double-blind, multi-dose trial of intra-muscular thiamin for the treatment of alcohol related brain injury, in alcohol dependent subjects who do not show any overt signs of Wernicke-Korsakoff syndrome.

Authors+Show Affiliations

Bowden S
Department of Psychology, University of Melbourne, Parkville, Victoria, Australia.
Bardenhagen F
No affiliation info available
Ambrose M
No affiliation info available
Whelan G
No affiliation info available

MeSH

AdultAlcohol Amnestic DisorderAlcoholismBrain InjuriesCognition DisordersDouble-Blind MethodHumansMaleMemory DisordersMiddle AgedNervous System DiseasesThiamineThiamine DeficiencyWernicke Encephalopathy

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

8974346

Citation

Bowden, S, et al. "Alcohol, Thiamin Deficiency, and Neuropsychological Disorders." Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement, vol. 2, 1994, pp. 267-72.
Bowden S, Bardenhagen F, Ambrose M, et al. Alcohol, thiamin deficiency, and neuropsychological disorders. Alcohol Alcohol Suppl. 1994;2:267-72.
Bowden, S., Bardenhagen, F., Ambrose, M., & Whelan, G. (1994). Alcohol, thiamin deficiency, and neuropsychological disorders. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement, 2, 267-72.
Bowden S, et al. Alcohol, Thiamin Deficiency, and Neuropsychological Disorders. Alcohol Alcohol Suppl. 1994;2:267-72. PubMed PMID: 8974346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol, thiamin deficiency, and neuropsychological disorders. AU - Bowden,S, AU - Bardenhagen,F, AU - Ambrose,M, AU - Whelan,G, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 267 EP - 72 JF - Alcohol and alcoholism (Oxford, Oxfordshire). Supplement JO - Alcohol Alcohol Suppl VL - 2 N2 - In this paper, two of the major themes in contemporary neuropsychological research are reviewed. These are the nature of cognitive impairment observed in alcohol related brain injury, and the cause or causes of alcohol related brain injury. Two experiments are briefly reported which address these issues. The first experiment concerns the nature of abilities which are involved in a test of memory (delayed matching to sample), which is fundamental to current experimental models of human amnesia. The second experiment involves preliminary data from a randomised, double-blind, multi-dose trial of intra-muscular thiamin for the treatment of alcohol related brain injury, in alcohol dependent subjects who do not show any overt signs of Wernicke-Korsakoff syndrome. SN - 1358-6173 UR - https://www.unboundmedicine.com/medline/citation/8974346/Alcohol_thiamin_deficiency_and_neuropsychological_disorders_ L2 - https://medlineplus.gov/neurologicdiseases.html DB - PRIME DP - Unbound Medicine ER -