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Pathological spectrum of alcoholic liver disease.
Alcohol Alcohol Suppl. 1994; 2:303-13.AA

Abstract

Alcoholic liver disease encompasses three main forms of liver injury: fatty change, alcoholic hepatitis and cirrhosis. However, there are many other types of injury, including perivenular fibrosis, venous occlusive lesions, microscopic cholangitis and chronic active hepatitis. The pathological spectrum is reviewed in this paper, and the contribution of other injurious agents to the pathological features is identified. Alcoholic liver disease can be mimicked by a variety of non-alcoholic liver diseases. However, features such as fatty liver with perivenular fibrosis, giant mitochondria, spotty hepatocyte necrosis, Mallory bodies, a micronodular pattern of cirrhosis, and iron deposition are strongly suggestive of an alcoholic aetiology. Correlation of clinical findings, and especially the alcohol history, and histopathological factors is necessary for the definitive diagnosis.

Authors+Show Affiliations

Histopathology Department, Flinders Medical Centre, Bedford Park, South Australia.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

8974350

Citation

Hall, P D.. "Pathological Spectrum of Alcoholic Liver Disease." Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement, vol. 2, 1994, pp. 303-13.
Hall PD. Pathological spectrum of alcoholic liver disease. Alcohol Alcohol Suppl. 1994;2:303-13.
Hall, P. D. (1994). Pathological spectrum of alcoholic liver disease. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement, 2, 303-13.
Hall PD. Pathological Spectrum of Alcoholic Liver Disease. Alcohol Alcohol Suppl. 1994;2:303-13. PubMed PMID: 8974350.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathological spectrum of alcoholic liver disease. A1 - Hall,P D, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 303 EP - 13 JF - Alcohol and alcoholism (Oxford, Oxfordshire). Supplement JO - Alcohol Alcohol Suppl VL - 2 N2 - Alcoholic liver disease encompasses three main forms of liver injury: fatty change, alcoholic hepatitis and cirrhosis. However, there are many other types of injury, including perivenular fibrosis, venous occlusive lesions, microscopic cholangitis and chronic active hepatitis. The pathological spectrum is reviewed in this paper, and the contribution of other injurious agents to the pathological features is identified. Alcoholic liver disease can be mimicked by a variety of non-alcoholic liver diseases. However, features such as fatty liver with perivenular fibrosis, giant mitochondria, spotty hepatocyte necrosis, Mallory bodies, a micronodular pattern of cirrhosis, and iron deposition are strongly suggestive of an alcoholic aetiology. Correlation of clinical findings, and especially the alcohol history, and histopathological factors is necessary for the definitive diagnosis. SN - 1358-6173 UR - https://www.unboundmedicine.com/medline/citation/8974350/Pathological_spectrum_of_alcoholic_liver_disease_ L2 - http://www.diseaseinfosearch.org/result/4280 DB - PRIME DP - Unbound Medicine ER -