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Decreased antibody response to influenza vaccine among nursing-home residents who received recalled vaccine--New York, 1996.
MMWR Morb Mortal Wkly Rep 1996; 45(50):1100-2MM

Abstract

Following a voluntary recall in November 1996 of 11 lots of Fluogen trivalent influenza vaccine (Parke-Davis Division, Warner Lambert Company, Morris Plains, New Jersey), the New York State Department of Health and CDC evaluated antibody response to the 1996-97 influenza vaccine among residents (n = 86) of three nursing homes who received recalled vaccine and among residents (n = 86) of three other nursing homes who received vaccine produced by a different manufacturer. The Fluogen lots were recalled because the monitored quantity of A/Nanchang/933/95(H3N2) hemagglutinin antigen in the 1996-97 influenza vaccine had declined since the vaccine initially was released; the reason for this decrease is unknown. The findings of this analysis indicate that, compared with elderly nursing-home residents who received influenza vaccine from a different manufacturer, residents who received Fluogen from recalled lots had moderately lower antibody responses to the influenza A/Nanchang/933/95(H3N2) component of the 1996-97 influenza vaccine.

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  • Publisher Full Text

    • Authors

    Centers for Disease Control and Prevention (CDC)
    No affiliation info available

    MeSH

    Antibodies, ViralHemagglutination Inhibition TestsHumansInfluenza A virusInfluenza B virusInfluenza VaccinesNew YorkNursing HomesVaccination

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    8999309

    Citation

    Centers for Disease Control and Prevention (CDC). "Decreased Antibody Response to Influenza Vaccine Among Nursing-home Residents Who Received Recalled vaccine--New York, 1996." MMWR. Morbidity and Mortality Weekly Report, vol. 45, no. 50, 1996, pp. 1100-2.
    Centers for Disease Control and Prevention (CDC). Decreased antibody response to influenza vaccine among nursing-home residents who received recalled vaccine--New York, 1996. MMWR Morb Mortal Wkly Rep. 1996;45(50):1100-2.
    Centers for Disease Control and Prevention (CDC). (1996). Decreased antibody response to influenza vaccine among nursing-home residents who received recalled vaccine--New York, 1996. MMWR. Morbidity and Mortality Weekly Report, 45(50), pp. 1100-2.
    Centers for Disease Control and Prevention (CDC). Decreased Antibody Response to Influenza Vaccine Among Nursing-home Residents Who Received Recalled vaccine--New York, 1996. MMWR Morb Mortal Wkly Rep. 1996 Dec 20;45(50):1100-2. PubMed PMID: 8999309.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Decreased antibody response to influenza vaccine among nursing-home residents who received recalled vaccine--New York, 1996. A1 - ,, PY - 1996/12/20/pubmed PY - 1996/12/20/medline PY - 1996/12/20/entrez SP - 1100 EP - 2 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb. Mortal. Wkly. Rep. VL - 45 IS - 50 N2 - Following a voluntary recall in November 1996 of 11 lots of Fluogen trivalent influenza vaccine (Parke-Davis Division, Warner Lambert Company, Morris Plains, New Jersey), the New York State Department of Health and CDC evaluated antibody response to the 1996-97 influenza vaccine among residents (n = 86) of three nursing homes who received recalled vaccine and among residents (n = 86) of three other nursing homes who received vaccine produced by a different manufacturer. The Fluogen lots were recalled because the monitored quantity of A/Nanchang/933/95(H3N2) hemagglutinin antigen in the 1996-97 influenza vaccine had declined since the vaccine initially was released; the reason for this decrease is unknown. The findings of this analysis indicate that, compared with elderly nursing-home residents who received influenza vaccine from a different manufacturer, residents who received Fluogen from recalled lots had moderately lower antibody responses to the influenza A/Nanchang/933/95(H3N2) component of the 1996-97 influenza vaccine. SN - 0149-2195 UR - https://www.unboundmedicine.com/medline/citation/8999309/Decreased_antibody_response_to_influenza_vaccine_among_nursing_home_residents_who_received_recalled_vaccine__New_York_1996_ L2 - http://www.cdc.gov/mmwr/preview/mmwrhtml/00044888.htm DB - PRIME DP - Unbound Medicine ER -