Abstract
Following a voluntary recall in November 1996 of 11 lots of Fluogen trivalent influenza vaccine (Parke-Davis Division, Warner Lambert Company, Morris Plains, New Jersey), the New York State Department of Health and CDC evaluated antibody response to the 1996-97 influenza vaccine among residents (n = 86) of three nursing homes who received recalled vaccine and among residents (n = 86) of three other nursing homes who received vaccine produced by a different manufacturer. The Fluogen lots were recalled because the monitored quantity of A/Nanchang/933/95(H3N2) hemagglutinin antigen in the 1996-97 influenza vaccine had declined since the vaccine initially was released; the reason for this decrease is unknown. The findings of this analysis indicate that, compared with elderly nursing-home residents who received influenza vaccine from a different manufacturer, residents who received Fluogen from recalled lots had moderately lower antibody responses to the influenza A/Nanchang/933/95(H3N2) component of the 1996-97 influenza vaccine.
TY - JOUR
T1 - Decreased antibody response to influenza vaccine among nursing-home residents who received recalled vaccine--New York, 1996.
A1 - ,,
PY - 1996/12/20/pubmed
PY - 1996/12/20/medline
PY - 1996/12/20/entrez
SP - 1100
EP - 2
JF - MMWR. Morbidity and mortality weekly report
JO - MMWR Morb Mortal Wkly Rep
VL - 45
IS - 50
N2 - Following a voluntary recall in November 1996 of 11 lots of Fluogen trivalent influenza vaccine (Parke-Davis Division, Warner Lambert Company, Morris Plains, New Jersey), the New York State Department of Health and CDC evaluated antibody response to the 1996-97 influenza vaccine among residents (n = 86) of three nursing homes who received recalled vaccine and among residents (n = 86) of three other nursing homes who received vaccine produced by a different manufacturer. The Fluogen lots were recalled because the monitored quantity of A/Nanchang/933/95(H3N2) hemagglutinin antigen in the 1996-97 influenza vaccine had declined since the vaccine initially was released; the reason for this decrease is unknown. The findings of this analysis indicate that, compared with elderly nursing-home residents who received influenza vaccine from a different manufacturer, residents who received Fluogen from recalled lots had moderately lower antibody responses to the influenza A/Nanchang/933/95(H3N2) component of the 1996-97 influenza vaccine.
SN - 0149-2195
UR - https://www.unboundmedicine.com/medline/citation/8999309/Decreased_antibody_response_to_influenza_vaccine_among_nursing_home_residents_who_received_recalled_vaccine__New_York_1996_
DB - PRIME
DP - Unbound Medicine
ER -