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A simple and sensitive quantitation of N,N-dimethyltryptamine by gas chromatography with surface ionization detection.
J Anal Toxicol. 1997 Jan-Feb; 21(1):36-40.JA

Abstract

A simple and sensitive method for determination of N,N-dimethyltryptamine (DMT) by gas chromatography (GC) with surface ionization detection (SID) is presented. Whole blood or urine, containing DMT and gramine (internal standard), was subjected to solid-phase extraction with a Sep-Pak C18 cartridge before analysis by GC-SID. The calibration curve was linear in the DMT range of 1.25-20 ng/mL blood or urine. The detection limit of DMT was about 0.5 ng/mL (10 pg on-column). The recovery of both DMT and gramine spiked in biological fluids was above 86%.

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Authors+Show Affiliations

Ishii A
Department of Legal Medicine, Hamamatsu University School of Medicine, Japan.
Seno H
No affiliation info available
Suzuki O
No affiliation info available
Hattori H
No affiliation info available
Kumazawa T
No affiliation info available

MeSH

CalibrationChromatography, GasHumansN,N-DimethyltryptamineSensitivity and SpecificitySubstance Abuse Detection

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9013290

Citation

Ishii, A, et al. "A Simple and Sensitive Quantitation of N,N-dimethyltryptamine By Gas Chromatography With Surface Ionization Detection." Journal of Analytical Toxicology, vol. 21, no. 1, 1997, pp. 36-40.
Ishii A, Seno H, Suzuki O, et al. A simple and sensitive quantitation of N,N-dimethyltryptamine by gas chromatography with surface ionization detection. J Anal Toxicol. 1997;21(1):36-40.
Ishii, A., Seno, H., Suzuki, O., Hattori, H., & Kumazawa, T. (1997). A simple and sensitive quantitation of N,N-dimethyltryptamine by gas chromatography with surface ionization detection. Journal of Analytical Toxicology, 21(1), 36-40.
Ishii A, et al. A Simple and Sensitive Quantitation of N,N-dimethyltryptamine By Gas Chromatography With Surface Ionization Detection. J Anal Toxicol. 1997 Jan-Feb;21(1):36-40. PubMed PMID: 9013290.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A simple and sensitive quantitation of N,N-dimethyltryptamine by gas chromatography with surface ionization detection. AU - Ishii,A, AU - Seno,H, AU - Suzuki,O, AU - Hattori,H, AU - Kumazawa,T, PY - 1997/1/1/pubmed PY - 1997/1/1/medline PY - 1997/1/1/entrez SP - 36 EP - 40 JF - Journal of analytical toxicology JO - J Anal Toxicol VL - 21 IS - 1 N2 - A simple and sensitive method for determination of N,N-dimethyltryptamine (DMT) by gas chromatography (GC) with surface ionization detection (SID) is presented. Whole blood or urine, containing DMT and gramine (internal standard), was subjected to solid-phase extraction with a Sep-Pak C18 cartridge before analysis by GC-SID. The calibration curve was linear in the DMT range of 1.25-20 ng/mL blood or urine. The detection limit of DMT was about 0.5 ng/mL (10 pg on-column). The recovery of both DMT and gramine spiked in biological fluids was above 86%. SN - 0146-4760 UR - https://www.unboundmedicine.com/medline/citation/9013290/A_simple_and_sensitive_quantitation_of_NN_dimethyltryptamine_by_gas_chromatography_with_surface_ionization_detection_ L2 - https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/21.1.36 DB - PRIME DP - Unbound Medicine ER -