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New therapeutic approaches to Alzheimer's disease.
J Clin Psychiatry. 1996; 57 Suppl 14:30-6.JC

Abstract

Therapeutic approaches to treat the cognitive impairment in dementia and to treat slow decline are making their way into clinical practice. Cholinergic agents are currently the most promising treatment, and several cholinesterase inhibitors will soon be available for prescription. As physicians learn more about dosing, side effects, and mechanisms of action, they can prescribe these drugs more efficiently. Evidence suggests that certain patients with dementia may be particularly responsive to such intervention, and other medications may enhance response. Current experimental approaches to slowing the rate of cognitive decline include the use of antioxidants, monoamine oxidase-B inhibitors, cholinesterase inhibitors, and anti-inflammatory agents. Psychosocial interventions appear to help delay institutionalization. Drugs that improve cognition also may affect behavioral symptoms and severe dementia as well as non-Alzheimer dementia.

Authors+Show Affiliations

Department of Psychiatry and the Behavioral Sciences, School of Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

9024334

Citation

Schneider, L S.. "New Therapeutic Approaches to Alzheimer's Disease." The Journal of Clinical Psychiatry, vol. 57 Suppl 14, 1996, pp. 30-6.
Schneider LS. New therapeutic approaches to Alzheimer's disease. J Clin Psychiatry. 1996;57 Suppl 14:30-6.
Schneider, L. S. (1996). New therapeutic approaches to Alzheimer's disease. The Journal of Clinical Psychiatry, 57 Suppl 14, 30-6.
Schneider LS. New Therapeutic Approaches to Alzheimer's Disease. J Clin Psychiatry. 1996;57 Suppl 14:30-6. PubMed PMID: 9024334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New therapeutic approaches to Alzheimer's disease. A1 - Schneider,L S, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 30 EP - 6 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 57 Suppl 14 N2 - Therapeutic approaches to treat the cognitive impairment in dementia and to treat slow decline are making their way into clinical practice. Cholinergic agents are currently the most promising treatment, and several cholinesterase inhibitors will soon be available for prescription. As physicians learn more about dosing, side effects, and mechanisms of action, they can prescribe these drugs more efficiently. Evidence suggests that certain patients with dementia may be particularly responsive to such intervention, and other medications may enhance response. Current experimental approaches to slowing the rate of cognitive decline include the use of antioxidants, monoamine oxidase-B inhibitors, cholinesterase inhibitors, and anti-inflammatory agents. Psychosocial interventions appear to help delay institutionalization. Drugs that improve cognition also may affect behavioral symptoms and severe dementia as well as non-Alzheimer dementia. SN - 0160-6689 UR - https://www.unboundmedicine.com/medline/citation/9024334/New_therapeutic_approaches_to_Alzheimer's_disease_ L2 - https://medlineplus.gov/alzheimersdisease.html DB - PRIME DP - Unbound Medicine ER -