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[Pancreatic beta-cell hyperplasia in adults. A clinical case].
Minerva Endocrinol 1996; 21(2):73-8ME

Abstract

The author describe a rare case of pancreatic beta-cell hyperplasia. The patient was referred to us because of serious hypoglycemic crises. During hospitalization, endogenous hyperinsulinism was confirmed by hematochemical and instrumental tests. AngioCT of the pancreas evidenced a small lesion of the corpus, suspected of insulinoma. The patient underwent a corpus caudalis pancreatectomy: a small nodule with histologic neuroendocrine traits was ablated. A few days after the operation, new symptomatic hypoglycemia appeared. The hormonal tests confirmed a recurrence of endogenous hyperinsulinism. The patient underwent a new operation for pancreaticoduodenectomy: histological examination confirmed a pancreatic beta-cells hyperplasia. This condition has to be taken into account in the differential diagnosis of post prandial hypoglycemia. Besides, the observation of an insulinoma doesn't exclude the presence of a diffused disorder of islet cells as in the case above described.

Authors+Show Affiliations

Divisione di Endocrinologia e Malattie del Ricambio, Ospedale Mauriziano Umberto I, Torino .No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ita

PubMed ID

9026684

Citation

Rossi, C, et al. "[Pancreatic Beta-cell Hyperplasia in Adults. a Clinical Case]." Minerva Endocrinologica, vol. 21, no. 2, 1996, pp. 73-8.
Rossi C, Grassi A, Torchio B, et al. [Pancreatic beta-cell hyperplasia in adults. A clinical case]. Minerva Endocrinol. 1996;21(2):73-8.
Rossi, C., Grassi, A., Torchio, B., Ravarino, N., Nasi, G., Gallone, G., & Fonzo, D. (1996). [Pancreatic beta-cell hyperplasia in adults. A clinical case]. Minerva Endocrinologica, 21(2), pp. 73-8.
Rossi C, et al. [Pancreatic Beta-cell Hyperplasia in Adults. a Clinical Case]. Minerva Endocrinol. 1996;21(2):73-8. PubMed PMID: 9026684.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pancreatic beta-cell hyperplasia in adults. A clinical case]. AU - Rossi,C, AU - Grassi,A, AU - Torchio,B, AU - Ravarino,N, AU - Nasi,G, AU - Gallone,G, AU - Fonzo,D, PY - 1996/6/1/pubmed PY - 1996/6/1/medline PY - 1996/6/1/entrez SP - 73 EP - 8 JF - Minerva endocrinologica JO - Minerva Endocrinol. VL - 21 IS - 2 N2 - The author describe a rare case of pancreatic beta-cell hyperplasia. The patient was referred to us because of serious hypoglycemic crises. During hospitalization, endogenous hyperinsulinism was confirmed by hematochemical and instrumental tests. AngioCT of the pancreas evidenced a small lesion of the corpus, suspected of insulinoma. The patient underwent a corpus caudalis pancreatectomy: a small nodule with histologic neuroendocrine traits was ablated. A few days after the operation, new symptomatic hypoglycemia appeared. The hormonal tests confirmed a recurrence of endogenous hyperinsulinism. The patient underwent a new operation for pancreaticoduodenectomy: histological examination confirmed a pancreatic beta-cells hyperplasia. This condition has to be taken into account in the differential diagnosis of post prandial hypoglycemia. Besides, the observation of an insulinoma doesn't exclude the presence of a diffused disorder of islet cells as in the case above described. SN - 0391-1977 UR - https://www.unboundmedicine.com/medline/citation/9026684/[Pancreatic_beta_cell_hyperplasia_in_adults__A_clinical_case]_ L2 - https://medlineplus.gov/hypoglycemia.html DB - PRIME DP - Unbound Medicine ER -