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[Hemodynamic studies on liver circulation with special reference to the hepatic artery].
Fortschr Med. 1977 Jul 21; 95(27):1741-4.FM

Abstract

Hepatic and systemic hemodynamics were studied in the rat under different experimental conditions. It could be demonstrated that the hepatic arterial blood flow in normal as well as in sick liver of animals is well regulated: for example by means of the venovasomotorical reaction (portoarterial interaction) and systemically by autoregulation. There exists an inverse correlation between arterial and portalvenous liver blood flow: As portal liver blood flow decreases hepatic arterial flow increases. Especially a marked increase of hepatic artery flow was found after portocaval end-to-side anastomosis. Yet, the hepatic artery flow improvement after portocaval shunt could not compensate the diverted portalvenous blood supply at all. In states of portal hypertension with a relevant portocaval collateral circulation, also after surgical portocaval shunt, the systemic circulation becomes more hyperdynamic. There also exists a remarkable relation between the extent of portocaval shunt flow to circulating blood volume, cardiac output and circulation time. Some correlates of the experimental findings with the altered hemodynamics in human liver cirrhosis were found and discussed from the viewpoint of portocaval shunt surgery in man.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

903058

Citation

Thiel, H. "[Hemodynamic Studies On Liver Circulation With Special Reference to the Hepatic Artery]." Fortschritte Der Medizin, vol. 95, no. 27, 1977, pp. 1741-4.
Thiel H. [Hemodynamic studies on liver circulation with special reference to the hepatic artery]. Fortschr Med. 1977;95(27):1741-4.
Thiel, H. (1977). [Hemodynamic studies on liver circulation with special reference to the hepatic artery]. Fortschritte Der Medizin, 95(27), 1741-4.
Thiel H. [Hemodynamic Studies On Liver Circulation With Special Reference to the Hepatic Artery]. Fortschr Med. 1977 Jul 21;95(27):1741-4. PubMed PMID: 903058.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hemodynamic studies on liver circulation with special reference to the hepatic artery]. A1 - Thiel,H, PY - 1977/7/21/pubmed PY - 1977/7/21/medline PY - 1977/7/21/entrez SP - 1741 EP - 4 JF - Fortschritte der Medizin JO - Fortschr Med VL - 95 IS - 27 N2 - Hepatic and systemic hemodynamics were studied in the rat under different experimental conditions. It could be demonstrated that the hepatic arterial blood flow in normal as well as in sick liver of animals is well regulated: for example by means of the venovasomotorical reaction (portoarterial interaction) and systemically by autoregulation. There exists an inverse correlation between arterial and portalvenous liver blood flow: As portal liver blood flow decreases hepatic arterial flow increases. Especially a marked increase of hepatic artery flow was found after portocaval end-to-side anastomosis. Yet, the hepatic artery flow improvement after portocaval shunt could not compensate the diverted portalvenous blood supply at all. In states of portal hypertension with a relevant portocaval collateral circulation, also after surgical portocaval shunt, the systemic circulation becomes more hyperdynamic. There also exists a remarkable relation between the extent of portocaval shunt flow to circulating blood volume, cardiac output and circulation time. Some correlates of the experimental findings with the altered hemodynamics in human liver cirrhosis were found and discussed from the viewpoint of portocaval shunt surgery in man. SN - 0015-8178 UR - https://www.unboundmedicine.com/medline/citation/903058/[Hemodynamic_studies_on_liver_circulation_with_special_reference_to_the_hepatic_artery]_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-B-1 DB - PRIME DP - Unbound Medicine ER -