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Prevention of NSAID-gastropathy.
Ital J Gastroenterol. 1996 Dec; 28 Suppl 4:33-6.IJ

Abstract

The role is reviewed of gastric antisecretory and mucosal protective drugs in the prevention of NSAID-induced gastric and duodenal mucosal lesions. The results of the randomized, double-blind, controlled trials show that misoprostol is the only antiulcer drug proven to be effective in the prevention of NSAID-induced gastric and duodenal ulcers as well as for reducing serious upper gastrointestinal complications (perforation and/or haemorrhage). However, recent data suggest that even omeprazole and high dose of H2-receptor antagonists may have a role in the prevention of NSAID-induced gastric and duodenal ulcerations.

Authors+Show Affiliations

Divisione di Gastroenterologia, Ospedale L. Sacco, Polo Universitario, Milano, Italy.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9032581

Citation

Ardizzone, S, and G Bianchi Porro. "Prevention of NSAID-gastropathy." The Italian Journal of Gastroenterology, vol. 28 Suppl 4, 1996, pp. 33-6.
Ardizzone S, Bianchi Porro G. Prevention of NSAID-gastropathy. Ital J Gastroenterol. 1996;28 Suppl 4:33-6.
Ardizzone, S., & Bianchi Porro, G. (1996). Prevention of NSAID-gastropathy. The Italian Journal of Gastroenterology, 28 Suppl 4, 33-6.
Ardizzone S, Bianchi Porro G. Prevention of NSAID-gastropathy. Ital J Gastroenterol. 1996;28 Suppl 4:33-6. PubMed PMID: 9032581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevention of NSAID-gastropathy. AU - Ardizzone,S, AU - Bianchi Porro,G, PY - 1996/12/1/pubmed PY - 1996/12/1/medline PY - 1996/12/1/entrez SP - 33 EP - 6 JF - The Italian journal of gastroenterology JO - Ital J Gastroenterol VL - 28 Suppl 4 N2 - The role is reviewed of gastric antisecretory and mucosal protective drugs in the prevention of NSAID-induced gastric and duodenal mucosal lesions. The results of the randomized, double-blind, controlled trials show that misoprostol is the only antiulcer drug proven to be effective in the prevention of NSAID-induced gastric and duodenal ulcers as well as for reducing serious upper gastrointestinal complications (perforation and/or haemorrhage). However, recent data suggest that even omeprazole and high dose of H2-receptor antagonists may have a role in the prevention of NSAID-induced gastric and duodenal ulcerations. SN - 0392-0623 UR - https://www.unboundmedicine.com/medline/citation/9032581/Prevention_of_NSAID_gastropathy_ DB - PRIME DP - Unbound Medicine ER -