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Wernicke-Korsakoff syndrome.
Postgrad Med J. 1997 Jan; 73(855):27-31.PM

Abstract

Alcohol abuse is one of the most serious problems in public health and the Wernicke-Korsakoff syndrome is one of the gravest consequences of alcoholism. The pathology is often undiagnosed in its less evident presentations, therefore an accurate diagnostic approach is a critical step in treatment planning. Treatment is based on restoration of thiamine, although this is insufficient to prevent the psychological decline of a great number of patients. The cognitive impact of the pathology is derived from the interaction of alcoholic neurotoxicity, thiamine deficiency and personal susceptibility. In this article, the literature concerning Wernicke-Korsakoff syndrome is reviewed.

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Authors+Show Affiliations

Zubaran C
Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Fernandes JG
No affiliation info available
Rodnight R
No affiliation info available

MeSH

Alcohol Amnestic DisorderAlcoholismHistory, 19th CenturyHumansMetabolic DiseasesPrognosisSyndromeThiamineThiamine DeficiencyWernicke Encephalopathy

Pub Type(s)

Historical Article
Journal Article
Review

Language

eng

PubMed ID

9039406

Citation

Zubaran, C, et al. "Wernicke-Korsakoff Syndrome." Postgraduate Medical Journal, vol. 73, no. 855, 1997, pp. 27-31.
Zubaran C, Fernandes JG, Rodnight R. Wernicke-Korsakoff syndrome. Postgrad Med J. 1997;73(855):27-31.
Zubaran, C., Fernandes, J. G., & Rodnight, R. (1997). Wernicke-Korsakoff syndrome. Postgraduate Medical Journal, 73(855), 27-31.
Zubaran C, Fernandes JG, Rodnight R. Wernicke-Korsakoff Syndrome. Postgrad Med J. 1997;73(855):27-31. PubMed PMID: 9039406.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Wernicke-Korsakoff syndrome. AU - Zubaran,C, AU - Fernandes,J G, AU - Rodnight,R, PY - 1997/1/1/pubmed PY - 1997/1/1/medline PY - 1997/1/1/entrez SP - 27 EP - 31 JF - Postgraduate medical journal JO - Postgrad Med J VL - 73 IS - 855 N2 - Alcohol abuse is one of the most serious problems in public health and the Wernicke-Korsakoff syndrome is one of the gravest consequences of alcoholism. The pathology is often undiagnosed in its less evident presentations, therefore an accurate diagnostic approach is a critical step in treatment planning. Treatment is based on restoration of thiamine, although this is insufficient to prevent the psychological decline of a great number of patients. The cognitive impact of the pathology is derived from the interaction of alcoholic neurotoxicity, thiamine deficiency and personal susceptibility. In this article, the literature concerning Wernicke-Korsakoff syndrome is reviewed. SN - 0032-5473 UR - https://www.unboundmedicine.com/medline/citation/9039406/Wernicke_Korsakoff_syndrome_ L2 - https://pmj.bmj.com/lookup/pmidlookup?view=long&pmid=9039406 DB - PRIME DP - Unbound Medicine ER -