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The surgical implications of primary hypercoagulable states.
J Ky Med Assoc. 1997 Feb; 95(2):67-72.JK

Abstract

Primary hypercoagulable states are hereditary disorders that result in arterial and venous thromboses. The purpose of this report is to present three patients with hypercoagulable states, and offer current guidelines for diagnosis and treatment. Primary hypercoagulable disorders such as antithrombin III, protein C and protein S deficiencies, fibrinolytic disorders such as decreased plasminogen levels and plasminogen activator deficiency, and antiphospholipid syndromes such as anticariolipin antibody and lupus anticoagulants will be reviewed. We will emphasize clinical characteristics that should prompt evaluation for hypercoagulation, appropriate laboratory tests for hypercoagulable disorders, and treatment. Other secondary and recently investigated hypercoagulable disorders, including heparin-associated thrombocytopenia, homocystinemia, lipoprotein (a), plasminogen activator inhibitor, and factor V Leiden, will also be reviewed.

Authors+Show Affiliations

Department of Surgery, University of Louisville School of Medicine, KY 40292, USA.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

9048471

Citation

Bergamini, T M., and J D. Richardson. "The Surgical Implications of Primary Hypercoagulable States." The Journal of the Kentucky Medical Association, vol. 95, no. 2, 1997, pp. 67-72.
Bergamini TM, Richardson JD. The surgical implications of primary hypercoagulable states. J Ky Med Assoc. 1997;95(2):67-72.
Bergamini, T. M., & Richardson, J. D. (1997). The surgical implications of primary hypercoagulable states. The Journal of the Kentucky Medical Association, 95(2), 67-72.
Bergamini TM, Richardson JD. The Surgical Implications of Primary Hypercoagulable States. J Ky Med Assoc. 1997;95(2):67-72. PubMed PMID: 9048471.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The surgical implications of primary hypercoagulable states. AU - Bergamini,T M, AU - Richardson,J D, PY - 1997/2/1/pubmed PY - 1997/2/1/medline PY - 1997/2/1/entrez SP - 67 EP - 72 JF - The Journal of the Kentucky Medical Association JO - J Ky Med Assoc VL - 95 IS - 2 N2 - Primary hypercoagulable states are hereditary disorders that result in arterial and venous thromboses. The purpose of this report is to present three patients with hypercoagulable states, and offer current guidelines for diagnosis and treatment. Primary hypercoagulable disorders such as antithrombin III, protein C and protein S deficiencies, fibrinolytic disorders such as decreased plasminogen levels and plasminogen activator deficiency, and antiphospholipid syndromes such as anticariolipin antibody and lupus anticoagulants will be reviewed. We will emphasize clinical characteristics that should prompt evaluation for hypercoagulation, appropriate laboratory tests for hypercoagulable disorders, and treatment. Other secondary and recently investigated hypercoagulable disorders, including heparin-associated thrombocytopenia, homocystinemia, lipoprotein (a), plasminogen activator inhibitor, and factor V Leiden, will also be reviewed. SN - 0023-0294 UR - https://www.unboundmedicine.com/medline/citation/9048471/The_surgical_implications_of_primary_hypercoagulable_states_ L2 - https://medlineplus.gov/bleedingdisorders.html DB - PRIME DP - Unbound Medicine ER -