Tags

Type your tag names separated by a space and hit enter

Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma.
Am J Ophthalmol. 1997 Mar; 123(3):320-7.AJ

Abstract

PURPOSE

To evaluate blood-flow parameters in three different groups of patients with primary open-angle glaucoma.

METHODS

Hemodynamic parameters in the ophthalmic artery, central retinal artery, central retinal vein, and lateral and medial short posterior ciliary arteries were evaluated by color Doppler imaging in 237 patients with primary open-angle glaucoma and 124 age-matched normal control subjects. Group A consisted of 56 patients with primary open-angle glaucoma with treated intraocular pressure higher than 20 mm Hg; group B, of 103 patients with primary open-angle glaucoma with progression of glaucomatous damage despite intraocular pressure of 21 mm Hg or less; and group C, of 78 patients with normal-tension glaucoma.

RESULTS

All patients showed a significant decrease in end-diastolic velocities (P < .01) and a significant increase in resistivity index (P < .05) in all arteries measured. Peak-systolic velocities were normal in the ophthalmic artery in all three groups. In the central retinal artery and the short posterior ciliary arteries, however, patients in groups B and C had significantly reduced peak-systolic velocity (P < .05) compared with normal control subjects. Peak-systolic velocity in group A did not differ significantly from that of normal control subjects. Maximal and minimal blood-flow velocities in the central retinal vein were significantly lower in groups B and C (P < .001) compared with normal control subjects. In group A, only minimal blood-flow velocity was significantly reduced (P < .05).

CONCLUSIONS

Hemodynamic parameters in the extraocular vessels are altered in patients with glaucoma. Reduced blood-flow velocities may be secondary as well as contributory to glaucomatous damage.

Authors+Show Affiliations

University Eye Clinic-Basel, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9063241

Citation

Kaiser, H J., et al. "Blood-flow Velocities of the Extraocular Vessels in Patients With High-tension and Normal-tension Primary Open-angle Glaucoma." American Journal of Ophthalmology, vol. 123, no. 3, 1997, pp. 320-7.
Kaiser HJ, Schoetzau A, Stümpfig D, et al. Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma. Am J Ophthalmol. 1997;123(3):320-7.
Kaiser, H. J., Schoetzau, A., Stümpfig, D., & Flammer, J. (1997). Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma. American Journal of Ophthalmology, 123(3), 320-7.
Kaiser HJ, et al. Blood-flow Velocities of the Extraocular Vessels in Patients With High-tension and Normal-tension Primary Open-angle Glaucoma. Am J Ophthalmol. 1997;123(3):320-7. PubMed PMID: 9063241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma. AU - Kaiser,H J, AU - Schoetzau,A, AU - Stümpfig,D, AU - Flammer,J, PY - 1997/3/1/pubmed PY - 1997/3/1/medline PY - 1997/3/1/entrez SP - 320 EP - 7 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 123 IS - 3 N2 - PURPOSE: To evaluate blood-flow parameters in three different groups of patients with primary open-angle glaucoma. METHODS: Hemodynamic parameters in the ophthalmic artery, central retinal artery, central retinal vein, and lateral and medial short posterior ciliary arteries were evaluated by color Doppler imaging in 237 patients with primary open-angle glaucoma and 124 age-matched normal control subjects. Group A consisted of 56 patients with primary open-angle glaucoma with treated intraocular pressure higher than 20 mm Hg; group B, of 103 patients with primary open-angle glaucoma with progression of glaucomatous damage despite intraocular pressure of 21 mm Hg or less; and group C, of 78 patients with normal-tension glaucoma. RESULTS: All patients showed a significant decrease in end-diastolic velocities (P < .01) and a significant increase in resistivity index (P < .05) in all arteries measured. Peak-systolic velocities were normal in the ophthalmic artery in all three groups. In the central retinal artery and the short posterior ciliary arteries, however, patients in groups B and C had significantly reduced peak-systolic velocity (P < .05) compared with normal control subjects. Peak-systolic velocity in group A did not differ significantly from that of normal control subjects. Maximal and minimal blood-flow velocities in the central retinal vein were significantly lower in groups B and C (P < .001) compared with normal control subjects. In group A, only minimal blood-flow velocity was significantly reduced (P < .05). CONCLUSIONS: Hemodynamic parameters in the extraocular vessels are altered in patients with glaucoma. Reduced blood-flow velocities may be secondary as well as contributory to glaucomatous damage. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/9063241/Blood_flow_velocities_of_the_extraocular_vessels_in_patients_with_high_tension_and_normal_tension_primary_open_angle_glaucoma_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(14)70127-8 DB - PRIME DP - Unbound Medicine ER -