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[Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation].
Fortschr Med. 1996 Nov 20; 114(32):439-43.FM

Abstract

In a randomized double-blind study involving 303 patients with alcoholic polyneuropathy the efficacy and tolerability of the combinations thiamine/pyridoxine, benfotiamine/pyridoxine, and the nucleotides of cytidine and uridine administered orally for 21 days were compared. Pain and paraesthesia, measured on a visual 10-cm-long analogue scale, as also pallaesthesia and the strength of the dorsiflexion and plantar flexors of the foot, clearly improved in all treatment groups. Clinically relevant differences in efficacy were not observed. All the drugs tested were well tolerated.

Authors+Show Affiliations

III. Psychiatrische Klinik, Klinik für Suchtkrankheiten, Schwerin.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial

Language

ger

PubMed ID

9064269

Citation

Kretschmar, C, et al. "[Medicamentous Therapy of Alcoholic Polyneuropathy. Randomized Double-blind Study Comparing 2 Vitamin B Preparations and a Nucleotide Preparation]." Fortschritte Der Medizin, vol. 114, no. 32, 1996, pp. 439-43.
Kretschmar C, Kaumeier S, Haase W. [Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation]. Fortschr Med. 1996;114(32):439-43.
Kretschmar, C., Kaumeier, S., & Haase, W. (1996). [Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation]. Fortschritte Der Medizin, 114(32), 439-43.
Kretschmar C, Kaumeier S, Haase W. [Medicamentous Therapy of Alcoholic Polyneuropathy. Randomized Double-blind Study Comparing 2 Vitamin B Preparations and a Nucleotide Preparation]. Fortschr Med. 1996 Nov 20;114(32):439-43. PubMed PMID: 9064269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation]. AU - Kretschmar,C, AU - Kaumeier,S, AU - Haase,W, PY - 1996/11/20/pubmed PY - 1996/11/20/medline PY - 1996/11/20/entrez SP - 439 EP - 43 JF - Fortschritte der Medizin JO - Fortschr Med VL - 114 IS - 32 N2 - In a randomized double-blind study involving 303 patients with alcoholic polyneuropathy the efficacy and tolerability of the combinations thiamine/pyridoxine, benfotiamine/pyridoxine, and the nucleotides of cytidine and uridine administered orally for 21 days were compared. Pain and paraesthesia, measured on a visual 10-cm-long analogue scale, as also pallaesthesia and the strength of the dorsiflexion and plantar flexors of the foot, clearly improved in all treatment groups. Clinically relevant differences in efficacy were not observed. All the drugs tested were well tolerated. SN - 0015-8178 UR - https://www.unboundmedicine.com/medline/citation/9064269/[Medicamentous_therapy_of_alcoholic_polyneuropathy__Randomized_double_blind_study_comparing_2_vitamin_B_preparations_and_a_nucleotide_preparation]_ L2 - https://medlineplus.gov/alcoholusedisorderaud.html DB - PRIME DP - Unbound Medicine ER -