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Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption.
Am J Gastroenterol. 1997 Mar; 92(3):485-9.AJ

Abstract

OBJECTIVES

Relationships of nutritional status with ethanol consumption and diet were studied in 33 chronic alcoholics with no clinical or laboratory evidence of liver disease.

METHODS

Nutritional assessment included subjective global assessment, weight-height index, body mass index, and serum albumin measurements. Dietary intake included estimates of daily intake of substrates, folic acid, vitamins B1, B5, B6, and B12. Circulating concentrations of folate, pyridoxal-phosphate and vitamin B12 were evaluated as well.

RESULTS

Only 18.1% of patients were considered malnourished, with body mass indices lower than those with an average or good nutritional status (p < 0.0001). Body weight was under 90% of the ideal in 8/33 (24%) patients. Serum albumin values were within normal range in all patients. In terms of calories provided by nonalcoholic substrates, protein, or vitamin intake, we observed no differences between well and poorly nourished individuals. However, malnourished alcoholics consumed significantly more ethanol (p = 0.01) and an inverse correlation was found between ethanol intake and weight-height index (r = -0.35; p = 0.03). Low circulating concentrations of pyridoxal-phosphate and red blood cell folate were found in 51.5% and 60.6% of alcoholics, respectively. These were not correlated with vitamin dietary intake or ethanol consumption, but there was a trend toward malnourished patients to present lower concentrations of red blood cell folate (p = 0.13).

CONCLUSIONS

Although over malnutrition is infrequent in this group of chronic alcoholics, specific vitamin deficiencies are present in a substantial proportion of patients and are more likely related to alcohol consumption.

Authors+Show Affiliations

Serviço de Gastrenterologia, Instituto Português de Oncologia Francisco Gentil de Lisboa, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9068475

Citation

Glória, L, et al. "Nutritional Deficiencies in Chronic Alcoholics: Relation to Dietary Intake and Alcohol Consumption." The American Journal of Gastroenterology, vol. 92, no. 3, 1997, pp. 485-9.
Glória L, Cravo M, Camilo ME, et al. Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. Am J Gastroenterol. 1997;92(3):485-9.
Glória, L., Cravo, M., Camilo, M. E., Resende, M., Cardoso, J. N., Oliveira, A. G., Leitão, C. N., & Mira, F. C. (1997). Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. The American Journal of Gastroenterology, 92(3), 485-9.
Glória L, et al. Nutritional Deficiencies in Chronic Alcoholics: Relation to Dietary Intake and Alcohol Consumption. Am J Gastroenterol. 1997;92(3):485-9. PubMed PMID: 9068475.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. AU - Glória,L, AU - Cravo,M, AU - Camilo,M E, AU - Resende,M, AU - Cardoso,J N, AU - Oliveira,A G, AU - Leitão,C N, AU - Mira,F C, PY - 1997/3/1/pubmed PY - 1997/3/1/medline PY - 1997/3/1/entrez SP - 485 EP - 9 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 92 IS - 3 N2 - OBJECTIVES: Relationships of nutritional status with ethanol consumption and diet were studied in 33 chronic alcoholics with no clinical or laboratory evidence of liver disease. METHODS: Nutritional assessment included subjective global assessment, weight-height index, body mass index, and serum albumin measurements. Dietary intake included estimates of daily intake of substrates, folic acid, vitamins B1, B5, B6, and B12. Circulating concentrations of folate, pyridoxal-phosphate and vitamin B12 were evaluated as well. RESULTS: Only 18.1% of patients were considered malnourished, with body mass indices lower than those with an average or good nutritional status (p < 0.0001). Body weight was under 90% of the ideal in 8/33 (24%) patients. Serum albumin values were within normal range in all patients. In terms of calories provided by nonalcoholic substrates, protein, or vitamin intake, we observed no differences between well and poorly nourished individuals. However, malnourished alcoholics consumed significantly more ethanol (p = 0.01) and an inverse correlation was found between ethanol intake and weight-height index (r = -0.35; p = 0.03). Low circulating concentrations of pyridoxal-phosphate and red blood cell folate were found in 51.5% and 60.6% of alcoholics, respectively. These were not correlated with vitamin dietary intake or ethanol consumption, but there was a trend toward malnourished patients to present lower concentrations of red blood cell folate (p = 0.13). CONCLUSIONS: Although over malnutrition is infrequent in this group of chronic alcoholics, specific vitamin deficiencies are present in a substantial proportion of patients and are more likely related to alcohol consumption. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/9068475/Nutritional_deficiencies_in_chronic_alcoholics:_relation_to_dietary_intake_and_alcohol_consumption_ L2 - https://medlineplus.gov/alcohol.html DB - PRIME DP - Unbound Medicine ER -