Tags

Type your tag names separated by a space and hit enter

Yeast metallothionein gene expression in response to metals and oxidative stress.
Methods. 1997 Mar; 11(3):289-99.M

Abstract

Metals and oxygen are chemically linked in biological systems. Metals and oxygen play important roles in enzymatic reactions, metabolism, and signal transduction; however, metals and oxygen react to form highly toxic oxygen-derived free radical species. In this review we focus on the use of yeast cells, as unicellular eukaryotic model systems, to conduct studies aimed at understanding fundamental mechanisms for the sensation and protective responses to toxic metals and oxygen-derived radicals via the activation of yeast metallothionein gene expression.

Links

Publisher Full Text

Authors+Show Affiliations

Liu XD
Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor 48109-0606, USA.
Thiele DJ
No affiliation info available

MeSH

AntioxidantsCandidaCarrier ProteinsDNA-Binding ProteinsFungal ProteinsGene Expression Regulation, FungalMetallothioneinMetalsOxidative StressSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTranscriptional Activation

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9073572

Citation

Liu, X D., and D J. Thiele. "Yeast Metallothionein Gene Expression in Response to Metals and Oxidative Stress." Methods (San Diego, Calif.), vol. 11, no. 3, 1997, pp. 289-99.
Liu XD, Thiele DJ. Yeast metallothionein gene expression in response to metals and oxidative stress. Methods. 1997;11(3):289-99.
Liu, X. D., & Thiele, D. J. (1997). Yeast metallothionein gene expression in response to metals and oxidative stress. Methods (San Diego, Calif.), 11(3), 289-99.
Liu XD, Thiele DJ. Yeast Metallothionein Gene Expression in Response to Metals and Oxidative Stress. Methods. 1997;11(3):289-99. PubMed PMID: 9073572.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Yeast metallothionein gene expression in response to metals and oxidative stress. AU - Liu,X D, AU - Thiele,D J, PY - 1997/3/1/pubmed PY - 1997/3/1/medline PY - 1997/3/1/entrez SP - 289 EP - 99 JF - Methods (San Diego, Calif.) JO - Methods VL - 11 IS - 3 N2 - Metals and oxygen are chemically linked in biological systems. Metals and oxygen play important roles in enzymatic reactions, metabolism, and signal transduction; however, metals and oxygen react to form highly toxic oxygen-derived free radical species. In this review we focus on the use of yeast cells, as unicellular eukaryotic model systems, to conduct studies aimed at understanding fundamental mechanisms for the sensation and protective responses to toxic metals and oxygen-derived radicals via the activation of yeast metallothionein gene expression. SN - 1046-2023 UR - https://www.unboundmedicine.com/medline/citation/9073572/Yeast_metallothionein_gene_expression_in_response_to_metals_and_oxidative_stress_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1046-2023(96)90423-5 DB - PRIME DP - Unbound Medicine ER -