Tags

Type your tag names separated by a space and hit enter

Combination therapy in Kala-azar.
J Assoc Physicians India. 1995 May; 43(5):319-20.JA

Abstract

128 untreated cases of Kala-azar were divided in 4 equal groups of 32, Group A was treated with Sodium Stibogluconate (SSG) in the dose of 20 mg/kg/body wt. for 30 days. Group B was treated SSG plus allopurinol in the dose of 20 mg/kg/body wt. orally in divided dosage for 30 days. Group C received SSG plus Ketoconazole 600 mg orally in divided dosage for 30 days. Group D in addition to SSG also received levamisole in single oral daily dose of 13 mg/kg/body wt. for 30 days. Response of Group B, C and D was compared to Group A. Results from this study revealed combination of allopurinol with SSG to be statistically not superior to SSG alone.

Authors+Show Affiliations

Singh NK
Kala-azar Research Centre, Barhmpura, Muzaffarpur.
Jha TK
No affiliation info available
Singh IJ
No affiliation info available
Jha S
No affiliation info available

MeSH

AdultAllopurinolAntimony Sodium GluconateAntiprotozoal AgentsDose-Response Relationship, DrugDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansKetoconazoleLeishmaniasis, VisceralLevamisoleMale

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

9081958

Citation

Singh, N K., et al. "Combination Therapy in Kala-azar." The Journal of the Association of Physicians of India, vol. 43, no. 5, 1995, pp. 319-20.
Singh NK, Jha TK, Singh IJ, et al. Combination therapy in Kala-azar. J Assoc Physicians India. 1995;43(5):319-20.
Singh, N. K., Jha, T. K., Singh, I. J., & Jha, S. (1995). Combination therapy in Kala-azar. The Journal of the Association of Physicians of India, 43(5), 319-20.
Singh NK, et al. Combination Therapy in Kala-azar. J Assoc Physicians India. 1995;43(5):319-20. PubMed PMID: 9081958.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combination therapy in Kala-azar. AU - Singh,N K, AU - Jha,T K, AU - Singh,I J, AU - Jha,S, PY - 1995/5/1/pubmed PY - 1995/5/1/medline PY - 1995/5/1/entrez SP - 319 EP - 20 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 43 IS - 5 N2 - 128 untreated cases of Kala-azar were divided in 4 equal groups of 32, Group A was treated with Sodium Stibogluconate (SSG) in the dose of 20 mg/kg/body wt. for 30 days. Group B was treated SSG plus allopurinol in the dose of 20 mg/kg/body wt. orally in divided dosage for 30 days. Group C received SSG plus Ketoconazole 600 mg orally in divided dosage for 30 days. Group D in addition to SSG also received levamisole in single oral daily dose of 13 mg/kg/body wt. for 30 days. Response of Group B, C and D was compared to Group A. Results from this study revealed combination of allopurinol with SSG to be statistically not superior to SSG alone. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/9081958/Combination_therapy_in_Kala_azar_ DB - PRIME DP - Unbound Medicine ER -