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Flavonol and chalcone ester glycosides from Bidens leucantha.
J Nat Prod. 1997 Mar; 60(3):270-3.JN

Abstract

Four new flavonol 7-O-glycosides 1-4 and a new chalcone ester glycoside 5 have been isolated from the leaves of Bidens leucantha along with four known chalcone ester glycosides 6-9. Their structures were elucidated using a combination of spectroscopic techniques. The in vitro anti-HIV activity of all the compounds was tested as part of our screening of potential anti-AIDS agents from medicinal plants. Although none of the flavonol glycosides was active, a moderate inhibitory effect on viral replication was exerted by chalcone ester glycoside 9.

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Authors+Show Affiliations

De Tommasi N
Centro Interdipartimentale di Chimica, Biologia e Technologie Farmaceutiche, Università degli Studi di Salerno, Italy.
Pizza C
No affiliation info available
Aquino R
No affiliation info available
Cumandà J
No affiliation info available
Mahmood N
No affiliation info available

MeSH

Anti-HIV AgentsCell LineChalconeChromatography, High Pressure LiquidFlavonoidsFlavonolsGlycosidesHIV-1HumansMagnetic Resonance SpectroscopyPlants, MedicinalSpectrometry, Mass, Fast Atom BombardmentVirus Replication

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9090869

Citation

De Tommasi, N, et al. "Flavonol and Chalcone Ester Glycosides From Bidens Leucantha." Journal of Natural Products, vol. 60, no. 3, 1997, pp. 270-3.
De Tommasi N, Pizza C, Aquino R, et al. Flavonol and chalcone ester glycosides from Bidens leucantha. J Nat Prod. 1997;60(3):270-3.
De Tommasi, N., Pizza, C., Aquino, R., Cumandà, J., & Mahmood, N. (1997). Flavonol and chalcone ester glycosides from Bidens leucantha. Journal of Natural Products, 60(3), 270-3.
De Tommasi N, et al. Flavonol and Chalcone Ester Glycosides From Bidens Leucantha. J Nat Prod. 1997;60(3):270-3. PubMed PMID: 9090869.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Flavonol and chalcone ester glycosides from Bidens leucantha. AU - De Tommasi,N, AU - Pizza,C, AU - Aquino,R, AU - Cumandà,J, AU - Mahmood,N, PY - 1997/3/1/pubmed PY - 1997/3/1/medline PY - 1997/3/1/entrez SP - 270 EP - 3 JF - Journal of natural products JO - J Nat Prod VL - 60 IS - 3 N2 - Four new flavonol 7-O-glycosides 1-4 and a new chalcone ester glycoside 5 have been isolated from the leaves of Bidens leucantha along with four known chalcone ester glycosides 6-9. Their structures were elucidated using a combination of spectroscopic techniques. The in vitro anti-HIV activity of all the compounds was tested as part of our screening of potential anti-AIDS agents from medicinal plants. Although none of the flavonol glycosides was active, a moderate inhibitory effect on viral replication was exerted by chalcone ester glycoside 9. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/9090869/Flavonol_and_chalcone_ester_glycosides_from_Bidens_leucantha_ L2 - https://doi.org/10.1021/np960572q DB - PRIME DP - Unbound Medicine ER -