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Primary sclerosing cholangitis: evolving concepts in diagnosis and treatment.
Dig Dis 1997 Jan-Apr; 15(1-2):23-41DD

Abstract

Primary sclerosing cholangitis is an increasingly recognized cause of chronic cholestatic liver disease. The etiology is unknown, although a number of immunologic and nonimmunologic factors have been considered. The most important diagnostic findings are diffuse irregularity and narrowing of extrahepatic and intrahepatic bile ducts. The prognosis varies, and a number of relatively unique complications may develop. No adequate treatment exists, although a number of potential treatments have been evaluated. Liver transplantation still remains the most appropriate treatment for end-stage disease. These various topics related to primary sclerosing cholangitis are reviewed.

Authors+Show Affiliations

Mayo Clinic, Rochester, Minn 55905, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9101128

Citation

Harnois, D M., and K D. Lindor. "Primary Sclerosing Cholangitis: Evolving Concepts in Diagnosis and Treatment." Digestive Diseases (Basel, Switzerland), vol. 15, no. 1-2, 1997, pp. 23-41.
Harnois DM, Lindor KD. Primary sclerosing cholangitis: evolving concepts in diagnosis and treatment. Dig Dis. 1997;15(1-2):23-41.
Harnois, D. M., & Lindor, K. D. (1997). Primary sclerosing cholangitis: evolving concepts in diagnosis and treatment. Digestive Diseases (Basel, Switzerland), 15(1-2), pp. 23-41.
Harnois DM, Lindor KD. Primary Sclerosing Cholangitis: Evolving Concepts in Diagnosis and Treatment. Dig Dis. 1997;15(1-2):23-41. PubMed PMID: 9101128.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primary sclerosing cholangitis: evolving concepts in diagnosis and treatment. AU - Harnois,D M, AU - Lindor,K D, PY - 1997/1/1/pubmed PY - 1997/1/1/medline PY - 1997/1/1/entrez SP - 23 EP - 41 JF - Digestive diseases (Basel, Switzerland) JO - Dig Dis VL - 15 IS - 1-2 N2 - Primary sclerosing cholangitis is an increasingly recognized cause of chronic cholestatic liver disease. The etiology is unknown, although a number of immunologic and nonimmunologic factors have been considered. The most important diagnostic findings are diffuse irregularity and narrowing of extrahepatic and intrahepatic bile ducts. The prognosis varies, and a number of relatively unique complications may develop. No adequate treatment exists, although a number of potential treatments have been evaluated. Liver transplantation still remains the most appropriate treatment for end-stage disease. These various topics related to primary sclerosing cholangitis are reviewed. SN - 0257-2753 UR - https://www.unboundmedicine.com/medline/citation/9101128/Primary_sclerosing_cholangitis:_evolving_concepts_in_diagnosis_and_treatment_ L2 - https://www.karger.com?DOI=10.1159/000171586 DB - PRIME DP - Unbound Medicine ER -