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[Hemoglobin, iron deficiency and anemia in pregnant women. Diagnostic aspects].
Tidsskr Nor Laegeforen. 1997 Mar 10; 117(7):962-6.TN

Abstract

Normal haemoglobin concentration in the trimesters of pregnancy can be considered to be 11-13 g/100 ml, 10-13 g/100 ml and 11-14 g/100 ml, respectively. High and low haemoglobin levels both indicate important pathophysiological changes. The authors discuss the use of serum-ferritin (S-ferritin), mean corpuscular volume (MCV) and erythrocyte protoporphyrin as diagnostic tools. S-ferritin, which is a reliable indicator of the iron status in the first trimester, becomes less reliable after the 20th week due to the physiological dilution of the plasma and a concurrent fall in haemoglobin and S-ferritin. Erythrocyte protoporphyrin is not influenced by the plasma dilution and can be used as a supplement to S-ferritin to assess iron deficiency. MCV can also be used to characterise the iron status. Decreases in MCV take time, however, which makes clinical interpretation difficult. S-ferritin measurement early in pregnancy is a reliable parameter for judging whether iron supplementation is necessary. Even if S-ferritin is influenced by the plasma dilution, a concentration below 15 microgram/l indicates iron deficiency in all stages of pregnancy.

Authors+Show Affiliations

Haram K
Kvinneklinikken, Haukeland Sykehus, Bergen.
Hervig T
No affiliation info available
Ulvik RJ
No affiliation info available

MeSH

Anemia, Iron-DeficiencyAnemia, MacrocyticErythrocyte IndicesFemaleFerritinsHemoglobinsHumansIronPregnancyPregnancy Complications, Hematologic

Pub Type(s)

English Abstract
Journal Article
Review

Language

nor

PubMed ID

9103009

Citation

Haram, K, et al. "[Hemoglobin, Iron Deficiency and Anemia in Pregnant Women. Diagnostic Aspects]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 117, no. 7, 1997, pp. 962-6.
Haram K, Hervig T, Ulvik RJ. [Hemoglobin, iron deficiency and anemia in pregnant women. Diagnostic aspects]. Tidsskr Nor Laegeforen. 1997;117(7):962-6.
Haram, K., Hervig, T., & Ulvik, R. J. (1997). [Hemoglobin, iron deficiency and anemia in pregnant women. Diagnostic aspects]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 117(7), 962-6.
Haram K, Hervig T, Ulvik RJ. [Hemoglobin, Iron Deficiency and Anemia in Pregnant Women. Diagnostic Aspects]. Tidsskr Nor Laegeforen. 1997 Mar 10;117(7):962-6. PubMed PMID: 9103009.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hemoglobin, iron deficiency and anemia in pregnant women. Diagnostic aspects]. AU - Haram,K, AU - Hervig,T, AU - Ulvik,R J, PY - 1997/3/10/pubmed PY - 1997/3/10/medline PY - 1997/3/10/entrez SP - 962 EP - 6 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 117 IS - 7 N2 - Normal haemoglobin concentration in the trimesters of pregnancy can be considered to be 11-13 g/100 ml, 10-13 g/100 ml and 11-14 g/100 ml, respectively. High and low haemoglobin levels both indicate important pathophysiological changes. The authors discuss the use of serum-ferritin (S-ferritin), mean corpuscular volume (MCV) and erythrocyte protoporphyrin as diagnostic tools. S-ferritin, which is a reliable indicator of the iron status in the first trimester, becomes less reliable after the 20th week due to the physiological dilution of the plasma and a concurrent fall in haemoglobin and S-ferritin. Erythrocyte protoporphyrin is not influenced by the plasma dilution and can be used as a supplement to S-ferritin to assess iron deficiency. MCV can also be used to characterise the iron status. Decreases in MCV take time, however, which makes clinical interpretation difficult. S-ferritin measurement early in pregnancy is a reliable parameter for judging whether iron supplementation is necessary. Even if S-ferritin is influenced by the plasma dilution, a concentration below 15 microgram/l indicates iron deficiency in all stages of pregnancy. SN - 0029-2001 UR - https://www.unboundmedicine.com/medline/citation/9103009/[Hemoglobin_iron_deficiency_and_anemia_in_pregnant_women__Diagnostic_aspects]_ L2 - http://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -