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Alcohol consumption and risk of pancreatic cancer.
Nutr Cancer 1997; 27(2):157-61NC

Abstract

The relation between pancreatic cancer and alcohol consumption was investigated in a case-control study conducted in Milan, Northern Italy, between 1983 and 1992 on 361 incident histologically confirmed cases and 997 controls admitted to hospital for acute nonneoplastic diseases apparently unrelated to alcohol and tobacco consumption. Compared with teetotalers, the multivariate odds ratio (OR) of pancreatic cancer, after adjustment for age, sex, education, smoking status, and history of diabetes, pancreatitis, and cholelithiasis, were 0.9 for alcohol drinkers and 0.9, 1.1, 1.4, and 1.1 for those who consumed up to four, more than four to seven, more than seven to eight, or more than eight alcoholic drinks per day; none of the estimates or the trend in risk was significant. OR were also close to unity in the separate analysis of wine, beer, and spirit intake, with no trend in risk, and no relationship was observed for duration of use (OR = 0.7 for > 40 yrs of use). No interaction was observed between pancreatic cancer and total alcohol intake in separate strata of age, sex, education, and smoking status. Thus the findings of the present study, on the basis of a population with relatively frequent and high alcohol consumption, provide epidemiologic evidence that even high alcohol intake does not appreciably modify the risk of pancreatic cancer.

Authors+Show Affiliations

Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9121943

Citation

Tavani, A, et al. "Alcohol Consumption and Risk of Pancreatic Cancer." Nutrition and Cancer, vol. 27, no. 2, 1997, pp. 157-61.
Tavani A, Pregnolato A, Negri E, et al. Alcohol consumption and risk of pancreatic cancer. Nutr Cancer. 1997;27(2):157-61.
Tavani, A., Pregnolato, A., Negri, E., & La Vecchia, C. (1997). Alcohol consumption and risk of pancreatic cancer. Nutrition and Cancer, 27(2), pp. 157-61.
Tavani A, et al. Alcohol Consumption and Risk of Pancreatic Cancer. Nutr Cancer. 1997;27(2):157-61. PubMed PMID: 9121943.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and risk of pancreatic cancer. AU - Tavani,A, AU - Pregnolato,A, AU - Negri,E, AU - La Vecchia,C, PY - 1997/1/1/pubmed PY - 1997/1/1/medline PY - 1997/1/1/entrez SP - 157 EP - 61 JF - Nutrition and cancer JO - Nutr Cancer VL - 27 IS - 2 N2 - The relation between pancreatic cancer and alcohol consumption was investigated in a case-control study conducted in Milan, Northern Italy, between 1983 and 1992 on 361 incident histologically confirmed cases and 997 controls admitted to hospital for acute nonneoplastic diseases apparently unrelated to alcohol and tobacco consumption. Compared with teetotalers, the multivariate odds ratio (OR) of pancreatic cancer, after adjustment for age, sex, education, smoking status, and history of diabetes, pancreatitis, and cholelithiasis, were 0.9 for alcohol drinkers and 0.9, 1.1, 1.4, and 1.1 for those who consumed up to four, more than four to seven, more than seven to eight, or more than eight alcoholic drinks per day; none of the estimates or the trend in risk was significant. OR were also close to unity in the separate analysis of wine, beer, and spirit intake, with no trend in risk, and no relationship was observed for duration of use (OR = 0.7 for > 40 yrs of use). No interaction was observed between pancreatic cancer and total alcohol intake in separate strata of age, sex, education, and smoking status. Thus the findings of the present study, on the basis of a population with relatively frequent and high alcohol consumption, provide epidemiologic evidence that even high alcohol intake does not appreciably modify the risk of pancreatic cancer. SN - 0163-5581 UR - https://www.unboundmedicine.com/medline/citation/9121943/Alcohol_consumption_and_risk_of_pancreatic_cancer_ L2 - http://www.tandfonline.com/doi/full/10.1080/01635589709514518 DB - PRIME DP - Unbound Medicine ER -