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[Treatment of amenorrhea-galactorrhea with bromo-ergocryptine. Apropos of 12 cases].
J Gynecol Obstet Biol Reprod (Paris). 1977 Jun; 6(4):537-46.JG

Abstract

The authors report the action of bromergocryptine in 12 patients who were suffering from a syndrome of amenorrhoea with galactorrhoea and hyperprolactinism. None of these 12 patients had a pituitary tumour; or else they had been operated on before treatment. Only in one case was the syndrome linked to taking oral contraceptives, which had been stopped more than six months previously. The dose of bromergocryptine was 5 mg. a day. If this dose fails it is possible to raise it after two months' observation. The galactorrhoea disappeared or markedly decreased in 8 out of the 12 cases. Ovulatory cycles started in 9 out of the 12. 5 of the women wanted a pregnancy: 4 succeeded and 2 of them have already been delivered of normal children. Bromergocryptine (CB 154) has thus proved itself to be remarkably effective in hyperprolactinism, not caused by a pituitary tumour, which gives rise to amenorrhoea and galactorrhoea. All the same, its long-term use, especially after stopping treatment, is still to be evaluated.

Authors

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Pub Type(s)

Journal Article

Language

fre

PubMed ID

915214

Citation

Hartemann, P, et al. "[Treatment of Amenorrhea-galactorrhea With Bromo-ergocryptine. Apropos of 12 Cases]." Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, vol. 6, no. 4, 1977, pp. 537-46.
Hartemann P, Leclere J, Groussin M, et al. [Treatment of amenorrhea-galactorrhea with bromo-ergocryptine. Apropos of 12 cases]. J Gynecol Obstet Biol Reprod (Paris). 1977;6(4):537-46.
Hartemann, P., Leclere, J., Groussin, M., Valdenaire, J. C., Maureira, J. J., Belleville, F., & Nabet, P. (1977). [Treatment of amenorrhea-galactorrhea with bromo-ergocryptine. Apropos of 12 cases]. Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, 6(4), 537-46.
Hartemann P, et al. [Treatment of Amenorrhea-galactorrhea With Bromo-ergocryptine. Apropos of 12 Cases]. J Gynecol Obstet Biol Reprod (Paris). 1977;6(4):537-46. PubMed PMID: 915214.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of amenorrhea-galactorrhea with bromo-ergocryptine. Apropos of 12 cases]. AU - Hartemann,P, AU - Leclere,J, AU - Groussin,M, AU - Valdenaire,J C, AU - Maureira,J J, AU - Belleville,F, AU - Nabet,P, PY - 1977/6/1/pubmed PY - 1977/6/1/medline PY - 1977/6/1/entrez SP - 537 EP - 46 JF - Journal de gynecologie, obstetrique et biologie de la reproduction JO - J Gynecol Obstet Biol Reprod (Paris) VL - 6 IS - 4 N2 - The authors report the action of bromergocryptine in 12 patients who were suffering from a syndrome of amenorrhoea with galactorrhoea and hyperprolactinism. None of these 12 patients had a pituitary tumour; or else they had been operated on before treatment. Only in one case was the syndrome linked to taking oral contraceptives, which had been stopped more than six months previously. The dose of bromergocryptine was 5 mg. a day. If this dose fails it is possible to raise it after two months' observation. The galactorrhoea disappeared or markedly decreased in 8 out of the 12 cases. Ovulatory cycles started in 9 out of the 12. 5 of the women wanted a pregnancy: 4 succeeded and 2 of them have already been delivered of normal children. Bromergocryptine (CB 154) has thus proved itself to be remarkably effective in hyperprolactinism, not caused by a pituitary tumour, which gives rise to amenorrhoea and galactorrhoea. All the same, its long-term use, especially after stopping treatment, is still to be evaluated. SN - 0368-2315 UR - https://www.unboundmedicine.com/medline/citation/915214/[Treatment_of_amenorrhea_galactorrhea_with_bromo_ergocryptine__Apropos_of_12_cases]_ DB - PRIME DP - Unbound Medicine ER -