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Association between alcohol use and smoking in adolescent and young adult twins: a bivariate genetic analysis.
Alcohol Clin Exp Res. 1997 May; 21(3):537-46.AC

Abstract

The association between alcohol use and smoking was examined in a large population-based sample of Dutch twins consisting of three age groups; young adolescent twins aged 12-14 years (n = 650 twin pairs), 15-16-years-old adolescent twins (n = 705 twin pairs), and young adult twins aged 17-25 years (n = 1266 twin pairs). For all three age groups, alcohol use and smoking were correlated (r = 0.5-0.6). Adolescents and young adults who smoked were more likely to drink alcohol than nonsmokers. The relation between alcohol use and smoking was also found within a twin pair; alcohol use in one twin was correlated with smoking in the cotwin. This finding suggested that familial factors contribute to the association between alcohol and tobacco use. With a bivariate genetic model, it was examined to what extent the comorbidity was due to genetic and environmental factors that predispose to both alcohol use and smoking. The genetic analyses showed that the underlying factors that influence alcohol and tobacco use and cause their association were different for adolescent and young adult twins. Initiation of alcohol use and smoking in adolescents (aged 12-16 years) was substantially influenced by the same shared environmental features. Alcohol and tobacco use in young adults were associated due to the same genetic risk factors.

Authors+Show Affiliations

Department of Psychonomics, Vrije Universiteit, Amsterdam, The Netherlands.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Twin Study

Language

eng

PubMed ID

9161615

Citation

Koopmans, J R., et al. "Association Between Alcohol Use and Smoking in Adolescent and Young Adult Twins: a Bivariate Genetic Analysis." Alcoholism, Clinical and Experimental Research, vol. 21, no. 3, 1997, pp. 537-46.
Koopmans JR, van Doornen LJ, Boomsma DI. Association between alcohol use and smoking in adolescent and young adult twins: a bivariate genetic analysis. Alcohol Clin Exp Res. 1997;21(3):537-46.
Koopmans, J. R., van Doornen, L. J., & Boomsma, D. I. (1997). Association between alcohol use and smoking in adolescent and young adult twins: a bivariate genetic analysis. Alcoholism, Clinical and Experimental Research, 21(3), 537-46.
Koopmans JR, van Doornen LJ, Boomsma DI. Association Between Alcohol Use and Smoking in Adolescent and Young Adult Twins: a Bivariate Genetic Analysis. Alcohol Clin Exp Res. 1997;21(3):537-46. PubMed PMID: 9161615.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association between alcohol use and smoking in adolescent and young adult twins: a bivariate genetic analysis. AU - Koopmans,J R, AU - van Doornen,L J, AU - Boomsma,D I, PY - 1997/5/1/pubmed PY - 1997/5/1/medline PY - 1997/5/1/entrez SP - 537 EP - 46 JF - Alcoholism, clinical and experimental research JO - Alcohol Clin Exp Res VL - 21 IS - 3 N2 - The association between alcohol use and smoking was examined in a large population-based sample of Dutch twins consisting of three age groups; young adolescent twins aged 12-14 years (n = 650 twin pairs), 15-16-years-old adolescent twins (n = 705 twin pairs), and young adult twins aged 17-25 years (n = 1266 twin pairs). For all three age groups, alcohol use and smoking were correlated (r = 0.5-0.6). Adolescents and young adults who smoked were more likely to drink alcohol than nonsmokers. The relation between alcohol use and smoking was also found within a twin pair; alcohol use in one twin was correlated with smoking in the cotwin. This finding suggested that familial factors contribute to the association between alcohol and tobacco use. With a bivariate genetic model, it was examined to what extent the comorbidity was due to genetic and environmental factors that predispose to both alcohol use and smoking. The genetic analyses showed that the underlying factors that influence alcohol and tobacco use and cause their association were different for adolescent and young adult twins. Initiation of alcohol use and smoking in adolescents (aged 12-16 years) was substantially influenced by the same shared environmental features. Alcohol and tobacco use in young adults were associated due to the same genetic risk factors. SN - 0145-6008 UR - https://www.unboundmedicine.com/medline/citation/9161615/Association_between_alcohol_use_and_smoking_in_adolescent_and_young_adult_twins:_a_bivariate_genetic_analysis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0145-6008&date=1997&volume=21&issue=3&spage=537 DB - PRIME DP - Unbound Medicine ER -