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Sedative use disorders in opiate-dependent patients: association with psychiatric and other substance use disorders.
J Nerv Ment Dis. 1997 May; 185(5):289-97.JN

Abstract

Opiate-dependent patients (N = 231), classified by sedative disorder status, were characterized according to DSM-IIIR on substance use and psychiatric disorders. Twenty-one percent currently (CUR+) had sedative use disorder, 39% had a history (HX+) of sedative use disorder, and 40% had no history (HX-) of this disorder. Several group differences were found. The HX+ and CUR+ groups had more lifetime drug use disorders (means = 4.5 and 4.3 vs. 3.2 in the HX- group), including alcohol, cannabis, stimulants, cocaine, and hallucinogens. In contrast, other psychiatric disorders (e.g., anxiety and depression) were low in prevalence and did not differ across groups, with the exception of a higher prevalence of antisocial personality disorder in the HX+ and CUR+ groups (39.6% and 38.5% vs. 17.9% in HX- group). The results suggest that sedative use disorder is related more to a severe spectrum of multiple substance abuse than it is to self-medication of underlying mood or anxiety disorders.

Authors+Show Affiliations

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

9171805

Citation

Chutuape, M A., et al. "Sedative Use Disorders in Opiate-dependent Patients: Association With Psychiatric and Other Substance Use Disorders." The Journal of Nervous and Mental Disease, vol. 185, no. 5, 1997, pp. 289-97.
Chutuape MA, Brooner RK, Stitzer M. Sedative use disorders in opiate-dependent patients: association with psychiatric and other substance use disorders. J Nerv Ment Dis. 1997;185(5):289-97.
Chutuape, M. A., Brooner, R. K., & Stitzer, M. (1997). Sedative use disorders in opiate-dependent patients: association with psychiatric and other substance use disorders. The Journal of Nervous and Mental Disease, 185(5), 289-97.
Chutuape MA, Brooner RK, Stitzer M. Sedative Use Disorders in Opiate-dependent Patients: Association With Psychiatric and Other Substance Use Disorders. J Nerv Ment Dis. 1997;185(5):289-97. PubMed PMID: 9171805.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sedative use disorders in opiate-dependent patients: association with psychiatric and other substance use disorders. AU - Chutuape,M A, AU - Brooner,R K, AU - Stitzer,M, PY - 1997/5/1/pubmed PY - 1997/5/1/medline PY - 1997/5/1/entrez SP - 289 EP - 97 JF - The Journal of nervous and mental disease JO - J Nerv Ment Dis VL - 185 IS - 5 N2 - Opiate-dependent patients (N = 231), classified by sedative disorder status, were characterized according to DSM-IIIR on substance use and psychiatric disorders. Twenty-one percent currently (CUR+) had sedative use disorder, 39% had a history (HX+) of sedative use disorder, and 40% had no history (HX-) of this disorder. Several group differences were found. The HX+ and CUR+ groups had more lifetime drug use disorders (means = 4.5 and 4.3 vs. 3.2 in the HX- group), including alcohol, cannabis, stimulants, cocaine, and hallucinogens. In contrast, other psychiatric disorders (e.g., anxiety and depression) were low in prevalence and did not differ across groups, with the exception of a higher prevalence of antisocial personality disorder in the HX+ and CUR+ groups (39.6% and 38.5% vs. 17.9% in HX- group). The results suggest that sedative use disorder is related more to a severe spectrum of multiple substance abuse than it is to self-medication of underlying mood or anxiety disorders. SN - 0022-3018 UR - https://www.unboundmedicine.com/medline/citation/9171805/Sedative_use_disorders_in_opiate_dependent_patients:_association_with_psychiatric_and_other_substance_use_disorders_ L2 - https://doi.org/10.1097/00005053-199705000-00002 DB - PRIME DP - Unbound Medicine ER -