Tags

Type your tag names separated by a space and hit enter

IgM and IgG in the human male genital tract.
Arch Androl. 1997 Jul-Aug; 39(1):45-53.AA

Abstract

In human seminal plasma it is possible to measure the levels of IgG and IgA, while IgM has been detected in trace amounts in only a few subjects. The source of these antibodies is unknown, although, under certain conditions, they seem to be produced in the sex tissues. Male human genital tract was processed for the immunohistochemical demonstration of IgG and IgM to verify the presence and the source of these antibodies. Only the epithelia of the prostate gland and urethra showed positivity to the immunohistochemical reaction, indicating the presence of IgM-secreting epithelial cells. Clusters of IgM- and IgG-positive immunocompetent cells were also observed in the subepithelial layers of all organs studied. The findings suggest that IgM are present in mucosal surfaces as a result of active secretion, as well as secretory IgA, whereas most of the IgG present in the human seminal plasma are probably derived by transudation process.

Authors+Show Affiliations

Department of Cytomorphology, University of Cagliari, Italy.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9202833

Citation

Sirigu, P, et al. "IgM and IgG in the Human Male Genital Tract." Archives of Andrology, vol. 39, no. 1, 1997, pp. 45-53.
Sirigu P, Perra MT, Maxia C, et al. IgM and IgG in the human male genital tract. Arch Androl. 1997;39(1):45-53.
Sirigu, P., Perra, M. T., Maxia, C., & Usai, E. (1997). IgM and IgG in the human male genital tract. Archives of Andrology, 39(1), 45-53.
Sirigu P, et al. IgM and IgG in the Human Male Genital Tract. Arch Androl. 1997 Jul-Aug;39(1):45-53. PubMed PMID: 9202833.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - IgM and IgG in the human male genital tract. AU - Sirigu,P, AU - Perra,M T, AU - Maxia,C, AU - Usai,E, PY - 1997/7/1/pubmed PY - 1997/7/1/medline PY - 1997/7/1/entrez SP - 45 EP - 53 JF - Archives of andrology JO - Arch. Androl. VL - 39 IS - 1 N2 - In human seminal plasma it is possible to measure the levels of IgG and IgA, while IgM has been detected in trace amounts in only a few subjects. The source of these antibodies is unknown, although, under certain conditions, they seem to be produced in the sex tissues. Male human genital tract was processed for the immunohistochemical demonstration of IgG and IgM to verify the presence and the source of these antibodies. Only the epithelia of the prostate gland and urethra showed positivity to the immunohistochemical reaction, indicating the presence of IgM-secreting epithelial cells. Clusters of IgM- and IgG-positive immunocompetent cells were also observed in the subepithelial layers of all organs studied. The findings suggest that IgM are present in mucosal surfaces as a result of active secretion, as well as secretory IgA, whereas most of the IgG present in the human seminal plasma are probably derived by transudation process. SN - 0148-5016 UR - https://www.unboundmedicine.com/medline/citation/9202833/IgM_and_IgG_in_the_human_male_genital_tract_ DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.