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A preliminary study of the analysis of Cannabis by supercritical fluid chromatography with atmospheric pressure chemical ionisation mass spectroscopic detection.
Sci Justice. 1997 Apr-Jun; 37(2):91-7.SJ

Abstract

A rapid method is described for the analysis of Cannabis products by supercritical fluid chromatography (SFC) coupled to atmospheric pressure chemical ionization-mass spectroscopic (APCI-MS) detection. The method had a shorter analysis time than GC-MS methods, without the need for derivatization prior to analysis. It was also faster than HPLC methods, with better resolution and definitive identification. Linearity of detector response to cannabidiol, delta 8-tetrahydrocannabinol, delta 9-tetrahydrocannabinol and cannabinol was established, the detection limits for mass on column being 0.55 ng, 1.20 ng, 0.69 ng and 2.10 ng respectively. The technique offers a means by which Cannabis products can be definitively identified in a single chromatographic run. Application to casework samples is described.

Authors+Show Affiliations

Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, United Kingdom.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9206314

Citation

Bäckström, B, et al. "A Preliminary Study of the Analysis of Cannabis By Supercritical Fluid Chromatography With Atmospheric Pressure Chemical Ionisation Mass Spectroscopic Detection." Science & Justice : Journal of the Forensic Science Society, vol. 37, no. 2, 1997, pp. 91-7.
Bäckström B, Cole MD, Carrott MJ, et al. A preliminary study of the analysis of Cannabis by supercritical fluid chromatography with atmospheric pressure chemical ionisation mass spectroscopic detection. Sci Justice. 1997;37(2):91-7.
Bäckström, B., Cole, M. D., Carrott, M. J., Jones, D. C., Davidson, G., & Coleman, K. (1997). A preliminary study of the analysis of Cannabis by supercritical fluid chromatography with atmospheric pressure chemical ionisation mass spectroscopic detection. Science & Justice : Journal of the Forensic Science Society, 37(2), 91-7.
Bäckström B, et al. A Preliminary Study of the Analysis of Cannabis By Supercritical Fluid Chromatography With Atmospheric Pressure Chemical Ionisation Mass Spectroscopic Detection. Sci Justice. 1997 Apr-Jun;37(2):91-7. PubMed PMID: 9206314.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A preliminary study of the analysis of Cannabis by supercritical fluid chromatography with atmospheric pressure chemical ionisation mass spectroscopic detection. AU - Bäckström,B, AU - Cole,M D, AU - Carrott,M J, AU - Jones,D C, AU - Davidson,G, AU - Coleman,K, PY - 1997/4/1/pubmed PY - 1997/4/1/medline PY - 1997/4/1/entrez SP - 91 EP - 7 JF - Science & justice : journal of the Forensic Science Society JO - Sci Justice VL - 37 IS - 2 N2 - A rapid method is described for the analysis of Cannabis products by supercritical fluid chromatography (SFC) coupled to atmospheric pressure chemical ionization-mass spectroscopic (APCI-MS) detection. The method had a shorter analysis time than GC-MS methods, without the need for derivatization prior to analysis. It was also faster than HPLC methods, with better resolution and definitive identification. Linearity of detector response to cannabidiol, delta 8-tetrahydrocannabinol, delta 9-tetrahydrocannabinol and cannabinol was established, the detection limits for mass on column being 0.55 ng, 1.20 ng, 0.69 ng and 2.10 ng respectively. The technique offers a means by which Cannabis products can be definitively identified in a single chromatographic run. Application to casework samples is described. SN - 1355-0306 UR - https://www.unboundmedicine.com/medline/citation/9206314/A_preliminary_study_of_the_analysis_of_Cannabis_by_supercritical_fluid_chromatography_with_atmospheric_pressure_chemical_ionisation_mass_spectroscopic_detection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1355-0306(97)72153-1 DB - PRIME DP - Unbound Medicine ER -