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Mesangial lupus nephritis with associated nephrotic syndrome.
J Am Soc Nephrol. 1997 Jul; 8(7):1199-204.JA

Abstract

Patients with mesangial proliferative lupus glomerulonephritis (World Health Organization class II) are generally believed to have only mild to moderate proteinuria and normal renal function. However, there have been several reports of patients with mesangial lupus with nephrotic-range proteinuria. In this report, we present two additional cases and review the literature. Of seven reported cases, persistent nephrotic syndrome was observed in four, morphologic transformation occurred in three, and all but one presented with varying degrees of azotemia. These cases reinforce the concept that in systemic lupus erythematosus, laboratory findings may not correlate well with the underlying glomerular lesion, and therefore, the renal biopsy is an essential clinical tool in the approach to lupus nephritis.

Authors+Show Affiliations

Section of Nephrology, University of Illinois at Chicago, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

9219171

Citation

Stankeviciute, N, et al. "Mesangial Lupus Nephritis With Associated Nephrotic Syndrome." Journal of the American Society of Nephrology : JASN, vol. 8, no. 7, 1997, pp. 1199-204.
Stankeviciute N, Jao W, Bakir A, et al. Mesangial lupus nephritis with associated nephrotic syndrome. J Am Soc Nephrol. 1997;8(7):1199-204.
Stankeviciute, N., Jao, W., Bakir, A., & Lash, J. P. (1997). Mesangial lupus nephritis with associated nephrotic syndrome. Journal of the American Society of Nephrology : JASN, 8(7), 1199-204.
Stankeviciute N, et al. Mesangial Lupus Nephritis With Associated Nephrotic Syndrome. J Am Soc Nephrol. 1997;8(7):1199-204. PubMed PMID: 9219171.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mesangial lupus nephritis with associated nephrotic syndrome. AU - Stankeviciute,N, AU - Jao,W, AU - Bakir,A, AU - Lash,J P, PY - 1997/7/1/pubmed PY - 1997/7/1/medline PY - 1997/7/1/entrez SP - 1199 EP - 204 JF - Journal of the American Society of Nephrology : JASN JO - J Am Soc Nephrol VL - 8 IS - 7 N2 - Patients with mesangial proliferative lupus glomerulonephritis (World Health Organization class II) are generally believed to have only mild to moderate proteinuria and normal renal function. However, there have been several reports of patients with mesangial lupus with nephrotic-range proteinuria. In this report, we present two additional cases and review the literature. Of seven reported cases, persistent nephrotic syndrome was observed in four, morphologic transformation occurred in three, and all but one presented with varying degrees of azotemia. These cases reinforce the concept that in systemic lupus erythematosus, laboratory findings may not correlate well with the underlying glomerular lesion, and therefore, the renal biopsy is an essential clinical tool in the approach to lupus nephritis. SN - 1046-6673 UR - https://www.unboundmedicine.com/medline/citation/9219171/Mesangial_lupus_nephritis_with_associated_nephrotic_syndrome_ L2 - https://jasn.asnjournals.org/cgi/pmidlookup?view=long&pmid=9219171 DB - PRIME DP - Unbound Medicine ER -