Tags

Type your tag names separated by a space and hit enter

[Respiratory inflammation].
Allerg Immunol (Paris). 1997 Mar; 29(3):75-6; discussion 82.AI

Abstract

Respiratory virus are the most frequent cause of asthma attacks, and are responsible for more than 80% of episodes of wheezing in children. Atopic subjects have a higher risk of respiratory virus infections, benign or severe, than healthy persons. In children older than 8 years, most respiratory infections are caused by rhinovirus (RV). RV colonizes the respiratory epithelium and provokes a symptomatic rhinitis by non-inflammatory routes (with non involvement of leucocytes). In the nose the most importance of these routes are nerves. In the lower respiratory airways, infection with RV causes an inflammatory reaction with persistence of eosinophils. IL-8 and the other cytokines produced by the infected epithelium extend the action of eosinophils and the inflammatory reaction. The viral/inflammatory pathway is an important new target for development of strategies for the prevention of asthma.

Authors+Show Affiliations

Médecine Universitaire, Southampton General Hospital, Angleterre.

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

9221015

Citation

Holgate, S T.. "[Respiratory Inflammation]." Allergie Et Immunologie, vol. 29, no. 3, 1997, pp. 75-6; discussion 82.
Holgate ST. [Respiratory inflammation]. Allerg Immunol (Paris). 1997;29(3):75-6; discussion 82.
Holgate, S. T. (1997). [Respiratory inflammation]. Allergie Et Immunologie, 29(3), 75-6; discussion 82.
Holgate ST. [Respiratory Inflammation]. Allerg Immunol (Paris). 1997;29(3):75-6; discussion 82. PubMed PMID: 9221015.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Respiratory inflammation]. A1 - Holgate,S T, PY - 1997/3/1/pubmed PY - 1997/3/1/medline PY - 1997/3/1/entrez SP - 75-6; discussion 82 JF - Allergie et immunologie JO - Allerg Immunol (Paris) VL - 29 IS - 3 N2 - Respiratory virus are the most frequent cause of asthma attacks, and are responsible for more than 80% of episodes of wheezing in children. Atopic subjects have a higher risk of respiratory virus infections, benign or severe, than healthy persons. In children older than 8 years, most respiratory infections are caused by rhinovirus (RV). RV colonizes the respiratory epithelium and provokes a symptomatic rhinitis by non-inflammatory routes (with non involvement of leucocytes). In the nose the most importance of these routes are nerves. In the lower respiratory airways, infection with RV causes an inflammatory reaction with persistence of eosinophils. IL-8 and the other cytokines produced by the infected epithelium extend the action of eosinophils and the inflammatory reaction. The viral/inflammatory pathway is an important new target for development of strategies for the prevention of asthma. SN - 0397-9148 UR - https://www.unboundmedicine.com/medline/citation/9221015/[Respiratory_inflammation]_ L2 - https://medlineplus.gov/asthma.html DB - PRIME DP - Unbound Medicine ER -