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Long-term effects of a very low calorie diet (Nutrilett) in obesity treatment. A prospective, randomized, comparison between VLCD and a hypocaloric diet+behavior modification and their combination.
Int J Obes Relat Metab Disord. 1997 Jul; 21(7):574-9.IJ

Abstract

OBJECTIVES

To compare weight loss on a balanced hypocaloric diet to that of a Very Low Calorie Diet (VLCD) after two months of treatment and to further compare 26 months of weight maintenance and safety with or without VLCD assistance in obese patients.

DESIGN

Prospective, randomized, controlled intervention trial, initially with two and later with three parallel groups.

SETTING

Swedish University out-patient obesity clinic.

SUBJECTS

Eighty-one obese patients of both gender with a BMI > or = 30 kg/m2 from the waiting list participated in a structured weight reduction + weight maintenance programme.

INTERVENTION

Twenty-seven patients (group A) were randomized to a balanced diet of 6720 kJ/d (1600 kcal/d) during the whole treatment period. The other patients (n = 54) were randomized to VLCD (Nutrilett) 1764 kJ/d (420 kcal/d) diet during the first two months. The VLCD treated patients were rerandomized after the initial treatment to the well balanced hypocaloric diet (6720 kJ/d) with (group C) or without (group B) 1 MJ of VLCD to be taken during the evening.

MAIN OUTCOME MEASURES

During the first two-month period, the mean body weight loss in the VLCD group was 18.9 +/- 7.1 kg compared to 7.2 +/- 4.8 kg in the diet treated group, with a similar relative fat loss assessed by bioimpedance of 68% and 76% respectively. The maintained weight loss in all groups after 28 months of treatment was 10.9 +/- 10.2 kg in the 52% who completed the programme. Weight losses and drop-out rates were similar in all three groups.

CONCLUSIONS

Twenty-four months weight maintenance and drop out rates are independent of whether the initial treatment commences with VLCD or a hypocaloric diet. One MJ nutrition powder taken freely does not affect 24 months weight maintenance on a hypocaloric (6.7 MJ/d) diet.

Authors+Show Affiliations

MEDDOC, Research Centre, Hørsholm, Denmark.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9226488

Citation

Ryttig, K R., et al. "Long-term Effects of a Very Low Calorie Diet (Nutrilett) in Obesity Treatment. a Prospective, Randomized, Comparison Between VLCD and a Hypocaloric Diet+behavior Modification and Their Combination." International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, vol. 21, no. 7, 1997, pp. 574-9.
Ryttig KR, Flaten H, Rössner S. Long-term effects of a very low calorie diet (Nutrilett) in obesity treatment. A prospective, randomized, comparison between VLCD and a hypocaloric diet+behavior modification and their combination. Int J Obes Relat Metab Disord. 1997;21(7):574-9.
Ryttig, K. R., Flaten, H., & Rössner, S. (1997). Long-term effects of a very low calorie diet (Nutrilett) in obesity treatment. A prospective, randomized, comparison between VLCD and a hypocaloric diet+behavior modification and their combination. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 21(7), 574-9.
Ryttig KR, Flaten H, Rössner S. Long-term Effects of a Very Low Calorie Diet (Nutrilett) in Obesity Treatment. a Prospective, Randomized, Comparison Between VLCD and a Hypocaloric Diet+behavior Modification and Their Combination. Int J Obes Relat Metab Disord. 1997;21(7):574-9. PubMed PMID: 9226488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term effects of a very low calorie diet (Nutrilett) in obesity treatment. A prospective, randomized, comparison between VLCD and a hypocaloric diet+behavior modification and their combination. AU - Ryttig,K R, AU - Flaten,H, AU - Rössner,S, PY - 1997/7/1/pubmed PY - 1997/7/1/medline PY - 1997/7/1/entrez SP - 574 EP - 9 JF - International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity JO - Int J Obes Relat Metab Disord VL - 21 IS - 7 N2 - OBJECTIVES: To compare weight loss on a balanced hypocaloric diet to that of a Very Low Calorie Diet (VLCD) after two months of treatment and to further compare 26 months of weight maintenance and safety with or without VLCD assistance in obese patients. DESIGN: Prospective, randomized, controlled intervention trial, initially with two and later with three parallel groups. SETTING: Swedish University out-patient obesity clinic. SUBJECTS: Eighty-one obese patients of both gender with a BMI > or = 30 kg/m2 from the waiting list participated in a structured weight reduction + weight maintenance programme. INTERVENTION: Twenty-seven patients (group A) were randomized to a balanced diet of 6720 kJ/d (1600 kcal/d) during the whole treatment period. The other patients (n = 54) were randomized to VLCD (Nutrilett) 1764 kJ/d (420 kcal/d) diet during the first two months. The VLCD treated patients were rerandomized after the initial treatment to the well balanced hypocaloric diet (6720 kJ/d) with (group C) or without (group B) 1 MJ of VLCD to be taken during the evening. MAIN OUTCOME MEASURES: During the first two-month period, the mean body weight loss in the VLCD group was 18.9 +/- 7.1 kg compared to 7.2 +/- 4.8 kg in the diet treated group, with a similar relative fat loss assessed by bioimpedance of 68% and 76% respectively. The maintained weight loss in all groups after 28 months of treatment was 10.9 +/- 10.2 kg in the 52% who completed the programme. Weight losses and drop-out rates were similar in all three groups. CONCLUSIONS: Twenty-four months weight maintenance and drop out rates are independent of whether the initial treatment commences with VLCD or a hypocaloric diet. One MJ nutrition powder taken freely does not affect 24 months weight maintenance on a hypocaloric (6.7 MJ/d) diet. UR - https://www.unboundmedicine.com/medline/citation/9226488/Long_term_effects_of_a_very_low_calorie_diet__Nutrilett__in_obesity_treatment__A_prospective_randomized_comparison_between_VLCD_and_a_hypocaloric_diet+behavior_modification_and_their_combination_ L2 - http://www.diseaseinfosearch.org/result/9028 DB - PRIME DP - Unbound Medicine ER -