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At what age does iron supplementation become necessary in low-birth-weight infants?
J Pediatr. 1977 Dec; 91(6):878-83.JPed

Abstract

Prevention of iron deficiency in low-birth-weight infants requires iron supplementation before neonatal iron stores are exhausted. In order to accurately determine when this depletion occurs, we measured the hemoglobin, mean corpuscular volume, serum iron/iron-binding capacity, and serum ferritin in 117 low-birth-weight infants (1,000 to 2,000 gm) from 0.5 until 6 months of age. All infants received banked breast milk in the hospital and breast milk or cow milk formula later; those with odd birth dates received 2 mg iron as ferrous sulfate/kg/day starting at 0.5 months; those with even birth dates received no additional iron unless they developed anemia. The results indicate that low-birth-weight infants who receive no supplemental iron may develop iron deficiency by three months of age and that a dose of iron of 2 mg/kg/day started at two weeks of age prevents iron deficiency without providing excess.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

925814

Citation

Lundström, U, et al. "At what Age Does Iron Supplementation Become Necessary in Low-birth-weight Infants?" The Journal of Pediatrics, vol. 91, no. 6, 1977, pp. 878-83.
Lundström U, Siimes MA, Dallman PR. At what age does iron supplementation become necessary in low-birth-weight infants? J Pediatr. 1977;91(6):878-83.
Lundström, U., Siimes, M. A., & Dallman, P. R. (1977). At what age does iron supplementation become necessary in low-birth-weight infants? The Journal of Pediatrics, 91(6), 878-83.
Lundström U, Siimes MA, Dallman PR. At what Age Does Iron Supplementation Become Necessary in Low-birth-weight Infants. J Pediatr. 1977;91(6):878-83. PubMed PMID: 925814.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - At what age does iron supplementation become necessary in low-birth-weight infants? AU - Lundström,U, AU - Siimes,M A, AU - Dallman,P R, PY - 1977/12/1/pubmed PY - 1977/12/1/medline PY - 1977/12/1/entrez SP - 878 EP - 83 JF - The Journal of pediatrics JO - J Pediatr VL - 91 IS - 6 N2 - Prevention of iron deficiency in low-birth-weight infants requires iron supplementation before neonatal iron stores are exhausted. In order to accurately determine when this depletion occurs, we measured the hemoglobin, mean corpuscular volume, serum iron/iron-binding capacity, and serum ferritin in 117 low-birth-weight infants (1,000 to 2,000 gm) from 0.5 until 6 months of age. All infants received banked breast milk in the hospital and breast milk or cow milk formula later; those with odd birth dates received 2 mg iron as ferrous sulfate/kg/day starting at 0.5 months; those with even birth dates received no additional iron unless they developed anemia. The results indicate that low-birth-weight infants who receive no supplemental iron may develop iron deficiency by three months of age and that a dose of iron of 2 mg/kg/day started at two weeks of age prevents iron deficiency without providing excess. SN - 0022-3476 UR - https://www.unboundmedicine.com/medline/citation/925814/At_what_age_does_iron_supplementation_become_necessary_in_low_birth_weight_infants L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3476(77)80881-0 DB - PRIME DP - Unbound Medicine ER -