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A 3-year review of meconium aspiration syndrome.
Singapore Med J. 1997 May; 38(5):205-8.SM

Abstract

AIM OF STUDY

To review the incidence, morbidity and mortality of Meconium Aspiration Syndrome (MAS). To identify possible predictors of MAS in newborns with thick meconium-stained amniotic fluid (MSAF) at delivery.

METHODOLOGY

Case records of babies with MSAF delivered in Singapore General Hospital from 1.1.1991 to 31.12.1993 were studied retrospectively.

RESULTS

In the study period, 1,893 babies (15% of live births) had MSAF and 174 babies (1.4% live births) developed MAS. The incidences of MAS in newborns with light, moderate and thick MSAF were 0.3%, 5.8% and 61% respectively. Complications associated with MAS were metabolic acidosis (52%), air leak syndrome (2%), persistent pulmonary hypertension (2%) and hypoxic ischaemic encephalopathy (0.5%). The mortality rate of babies with MAS was 2%. Newborns with thick MSAF were more likely to develop MAS if they were males, small-for- gestational-age, had fetal distress and meconium was sucked from the trachea at birth.

CONCLUSION

Vigilant perinatal monitoring of high risk babies with MSAF and proper resuscitation at birth would help reduce the incidence of MAS and its associated complications.

Authors+Show Affiliations

Yong YP
Department of Neonatology, Singapore General Hospital, Singapore.
Ho LY
No affiliation info available

MeSH

FemaleHospital MortalityHospitals, GeneralHumansIncidenceInfant, NewbornIntensive Care, NeonatalMaleMeconium Aspiration SyndromeMorbidityPredictive Value of TestsRetrospective StudiesRisk FactorsSingapore

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9259600

Citation

Yong, Y P., and L Y. Ho. "A 3-year Review of Meconium Aspiration Syndrome." Singapore Medical Journal, vol. 38, no. 5, 1997, pp. 205-8.
Yong YP, Ho LY. A 3-year review of meconium aspiration syndrome. Singapore Med J. 1997;38(5):205-8.
Yong, Y. P., & Ho, L. Y. (1997). A 3-year review of meconium aspiration syndrome. Singapore Medical Journal, 38(5), 205-8.
Yong YP, Ho LY. A 3-year Review of Meconium Aspiration Syndrome. Singapore Med J. 1997;38(5):205-8. PubMed PMID: 9259600.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A 3-year review of meconium aspiration syndrome. AU - Yong,Y P, AU - Ho,L Y, PY - 1997/5/1/pubmed PY - 1997/5/1/medline PY - 1997/5/1/entrez SP - 205 EP - 8 JF - Singapore medical journal JO - Singapore Med J VL - 38 IS - 5 N2 - AIM OF STUDY: To review the incidence, morbidity and mortality of Meconium Aspiration Syndrome (MAS). To identify possible predictors of MAS in newborns with thick meconium-stained amniotic fluid (MSAF) at delivery. METHODOLOGY: Case records of babies with MSAF delivered in Singapore General Hospital from 1.1.1991 to 31.12.1993 were studied retrospectively. RESULTS: In the study period, 1,893 babies (15% of live births) had MSAF and 174 babies (1.4% live births) developed MAS. The incidences of MAS in newborns with light, moderate and thick MSAF were 0.3%, 5.8% and 61% respectively. Complications associated with MAS were metabolic acidosis (52%), air leak syndrome (2%), persistent pulmonary hypertension (2%) and hypoxic ischaemic encephalopathy (0.5%). The mortality rate of babies with MAS was 2%. Newborns with thick MSAF were more likely to develop MAS if they were males, small-for- gestational-age, had fetal distress and meconium was sucked from the trachea at birth. CONCLUSION: Vigilant perinatal monitoring of high risk babies with MSAF and proper resuscitation at birth would help reduce the incidence of MAS and its associated complications. SN - 0037-5675 UR - https://www.unboundmedicine.com/medline/citation/9259600/A_3_year_review_of_meconium_aspiration_syndrome_ L2 - http://www.diseaseinfosearch.org/result/4539 DB - PRIME DP - Unbound Medicine ER -