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Synergism of lorazepam and electroconvulsive therapy in the treatment of catatonia.
Biol Psychiatry. 1997 Sep 01; 42(5):375-81.BP

Abstract

Electroconvulsive therapy (ECT) and lorazepam are effective treatments for catatonia. ECT combined with benzodiazepines has been associated with reduced efficacy and efficiency and therefore is not recommended in the routine practice of ECT. We report 5 prospectively identified cases of catatonia treated either sequentially or concurrently with lorazepam and ECT. In each case, the combination of lorazepam with ECT was superior to monotherapy. This apparent synergism, its possible mechanisms, and its implications for treating catatonia are discussed.

Authors+Show Affiliations

Department of Psychiatry and Behavioral Sciences, SUNY Stony Brook 11794, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Clinical Trial
Journal Article

Language

eng

PubMed ID

9276078

Citation

Petrides, G, et al. "Synergism of Lorazepam and Electroconvulsive Therapy in the Treatment of Catatonia." Biological Psychiatry, vol. 42, no. 5, 1997, pp. 375-81.
Petrides G, Divadeenam KM, Bush G, et al. Synergism of lorazepam and electroconvulsive therapy in the treatment of catatonia. Biol Psychiatry. 1997;42(5):375-81.
Petrides, G., Divadeenam, K. M., Bush, G., & Francis, A. (1997). Synergism of lorazepam and electroconvulsive therapy in the treatment of catatonia. Biological Psychiatry, 42(5), 375-81.
Petrides G, et al. Synergism of Lorazepam and Electroconvulsive Therapy in the Treatment of Catatonia. Biol Psychiatry. 1997 Sep 1;42(5):375-81. PubMed PMID: 9276078.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synergism of lorazepam and electroconvulsive therapy in the treatment of catatonia. AU - Petrides,G, AU - Divadeenam,K M, AU - Bush,G, AU - Francis,A, PY - 1997/9/1/pubmed PY - 1997/9/1/medline PY - 1997/9/1/entrez SP - 375 EP - 81 JF - Biological psychiatry JO - Biol. Psychiatry VL - 42 IS - 5 N2 - Electroconvulsive therapy (ECT) and lorazepam are effective treatments for catatonia. ECT combined with benzodiazepines has been associated with reduced efficacy and efficiency and therefore is not recommended in the routine practice of ECT. We report 5 prospectively identified cases of catatonia treated either sequentially or concurrently with lorazepam and ECT. In each case, the combination of lorazepam with ECT was superior to monotherapy. This apparent synergism, its possible mechanisms, and its implications for treating catatonia are discussed. SN - 0006-3223 UR - https://www.unboundmedicine.com/medline/citation/9276078/Synergism_of_lorazepam_and_electroconvulsive_therapy_in_the_treatment_of_catatonia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0006-3223(96)00378-2 DB - PRIME DP - Unbound Medicine ER -