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Proteinase-mediated insect resistance to Bacillus thuringiensis toxins.
J Biol Chem. 1997 Sep 19; 272(38):23473-6.JB

Abstract

Two Bacillus thuringiensis (Bt)-resistant strains of the Indianmeal moth, Plodia interpunctella, lack a major gut proteinase that activates Bt protoxins. The absence of this enzyme is genetically linked to larval survival on Bt-treated diets. When considered with previous data supporting the existence of receptor-mediated insect resistance to Bt, these results provide evidence that insect adaptation to these toxins occurs through multiple physiological mechanisms, which complicate efforts to prevent or manage resistance to Bt toxins in insect control programs.

Authors+Show Affiliations

United States Grain Marketing Research Laboratory, United States Department of Agriculture, Agricultural Research Service, Manhattan, Kansas 66502-2736, USA. bso@ksu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9295279

Citation

Oppert, B, et al. "Proteinase-mediated Insect Resistance to Bacillus Thuringiensis Toxins." The Journal of Biological Chemistry, vol. 272, no. 38, 1997, pp. 23473-6.
Oppert B, Kramer KJ, Beeman RW, et al. Proteinase-mediated insect resistance to Bacillus thuringiensis toxins. J Biol Chem. 1997;272(38):23473-6.
Oppert, B., Kramer, K. J., Beeman, R. W., Johnson, D., & McGaughey, W. H. (1997). Proteinase-mediated insect resistance to Bacillus thuringiensis toxins. The Journal of Biological Chemistry, 272(38), 23473-6.
Oppert B, et al. Proteinase-mediated Insect Resistance to Bacillus Thuringiensis Toxins. J Biol Chem. 1997 Sep 19;272(38):23473-6. PubMed PMID: 9295279.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Proteinase-mediated insect resistance to Bacillus thuringiensis toxins. AU - Oppert,B, AU - Kramer,K J, AU - Beeman,R W, AU - Johnson,D, AU - McGaughey,W H, PY - 1997/9/20/pubmed PY - 1997/9/20/medline PY - 1997/9/20/entrez SP - 23473 EP - 6 JF - The Journal of biological chemistry JO - J Biol Chem VL - 272 IS - 38 N2 - Two Bacillus thuringiensis (Bt)-resistant strains of the Indianmeal moth, Plodia interpunctella, lack a major gut proteinase that activates Bt protoxins. The absence of this enzyme is genetically linked to larval survival on Bt-treated diets. When considered with previous data supporting the existence of receptor-mediated insect resistance to Bt, these results provide evidence that insect adaptation to these toxins occurs through multiple physiological mechanisms, which complicate efforts to prevent or manage resistance to Bt toxins in insect control programs. SN - 0021-9258 UR - https://www.unboundmedicine.com/medline/citation/9295279/Proteinase_mediated_insect_resistance_to_Bacillus_thuringiensis_toxins_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9258(19)65811-4 DB - PRIME DP - Unbound Medicine ER -