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Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk.
Eur J Clin Nutr. 1997 Sep; 51(9):625-32.EJ

Abstract

OBJECTIVES

This study investigated, on 53 Australians consuming a typical Western diet, the relationship between dietary intake, faecal excretion of carbohydrate and changes in faecal markers believed to be relevant to colon cancer risk, for example faecal output, transit time and concentrations of phenols, ammonia and butyrate.

DESIGN

Fifty-three subjects consuming their usual diet were asked to record and weigh all food consumed for a seven day period, and to collect faeces for three days during this period.

SETTING

Geelong, Victoria, Australia.

SUBJECTS

All volunteers were either staff and students of the university, or associates of the authors.

INTERVENTIONS

None.

RESULTS

Volunteers had the following dietary intakes of carbohydrate (g/d; mean +/- s.d.); starch 131 +/- 41 (including resistant starch (RS), 5 +/- 2), sugar 108 +/- 37 and non-starch polysaccharides (NSP) 14 +/- 7. Daily faecal output was 127 +/- 70 g and transit time 47 +/- 19 h. Analysis of faecal samples found 0.8 +/- 1.2 g RS and significant relationship with the concentration (mmol/L) of butyrate excreted n faeces (r = 0.34, P < 0.05). Dietary intake of RS was associated with higher concentrations of faecal ammonia (r = 0.34, P < 0.05), but this association was reversed when RS was combined with NSP in the diet (r = 0.07, NS). In contrast to dietary intake, the faecal excretion of RS was negatively related to faecal ammonia concentration (r = -0.40, P < 0.01) and positively related to faecal output (r = 0.64, P < 0.01). Individuals who consumed more NSP in their diet (19 +/- 7 g/d) excreted more than 150 g faeces per day and had higher quantities of faecal-RS and -NSP; faster transit times; higher concentrations of short chain fatty acids and lower concentrations of potentially harmful ammonia and phenols.

CONCLUSIONS

The combination of RS and NSP in the colon may be required to achieve an optimal luminal environment conducive to 'colonic health'. The results also support the suggestion that faecal output (< or > 150 g/d) may provide a useful index of colon cancer risk. High faecal outputs are achieved through higher intakes of NSP (the major component of dietary fibre).

Authors+Show Affiliations

Deakin University School of Nutrition and Public Health, Geelong, Victoria, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9306090

Citation

Birkett, A M., et al. "Dietary Intake and Faecal Excretion of Carbohydrate By Australians: Importance of Achieving Stool Weights Greater Than 150 G to Improve Faecal Markers Relevant to Colon Cancer Risk." European Journal of Clinical Nutrition, vol. 51, no. 9, 1997, pp. 625-32.
Birkett AM, Jones GP, de Silva AM, et al. Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. Eur J Clin Nutr. 1997;51(9):625-32.
Birkett, A. M., Jones, G. P., de Silva, A. M., Young, G. P., & Muir, J. G. (1997). Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. European Journal of Clinical Nutrition, 51(9), 625-32.
Birkett AM, et al. Dietary Intake and Faecal Excretion of Carbohydrate By Australians: Importance of Achieving Stool Weights Greater Than 150 G to Improve Faecal Markers Relevant to Colon Cancer Risk. Eur J Clin Nutr. 1997;51(9):625-32. PubMed PMID: 9306090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. AU - Birkett,A M, AU - Jones,G P, AU - de Silva,A M, AU - Young,G P, AU - Muir,J G, PY - 1997/11/5/pubmed PY - 1997/11/5/medline PY - 1997/11/5/entrez SP - 625 EP - 32 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 51 IS - 9 N2 - OBJECTIVES: This study investigated, on 53 Australians consuming a typical Western diet, the relationship between dietary intake, faecal excretion of carbohydrate and changes in faecal markers believed to be relevant to colon cancer risk, for example faecal output, transit time and concentrations of phenols, ammonia and butyrate. DESIGN: Fifty-three subjects consuming their usual diet were asked to record and weigh all food consumed for a seven day period, and to collect faeces for three days during this period. SETTING: Geelong, Victoria, Australia. SUBJECTS: All volunteers were either staff and students of the university, or associates of the authors. INTERVENTIONS: None. RESULTS: Volunteers had the following dietary intakes of carbohydrate (g/d; mean +/- s.d.); starch 131 +/- 41 (including resistant starch (RS), 5 +/- 2), sugar 108 +/- 37 and non-starch polysaccharides (NSP) 14 +/- 7. Daily faecal output was 127 +/- 70 g and transit time 47 +/- 19 h. Analysis of faecal samples found 0.8 +/- 1.2 g RS and significant relationship with the concentration (mmol/L) of butyrate excreted n faeces (r = 0.34, P < 0.05). Dietary intake of RS was associated with higher concentrations of faecal ammonia (r = 0.34, P < 0.05), but this association was reversed when RS was combined with NSP in the diet (r = 0.07, NS). In contrast to dietary intake, the faecal excretion of RS was negatively related to faecal ammonia concentration (r = -0.40, P < 0.01) and positively related to faecal output (r = 0.64, P < 0.01). Individuals who consumed more NSP in their diet (19 +/- 7 g/d) excreted more than 150 g faeces per day and had higher quantities of faecal-RS and -NSP; faster transit times; higher concentrations of short chain fatty acids and lower concentrations of potentially harmful ammonia and phenols. CONCLUSIONS: The combination of RS and NSP in the colon may be required to achieve an optimal luminal environment conducive to 'colonic health'. The results also support the suggestion that faecal output (< or > 150 g/d) may provide a useful index of colon cancer risk. High faecal outputs are achieved through higher intakes of NSP (the major component of dietary fibre). SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/9306090/Dietary_intake_and_faecal_excretion_of_carbohydrate_by_Australians:_importance_of_achieving_stool_weights_greater_than_150_g_to_improve_faecal_markers_relevant_to_colon_cancer_risk_ L2 - https://doi.org/10.1038/sj.ejcn.1600456 DB - PRIME DP - Unbound Medicine ER -