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Effect of bromo-ergocryptine on serum hPRL, hLH, hFSH, and estradiol 17-beta in women with galactorrhea-amenorrhea.
Obstet Gynecol. 1976 Jul; 48(1):84-9.OG

Abstract

Fourteen women with amenorrhea-galactorrhea were treated with bromo-ergocryptine. Serum prolactin hPRL, hLH, hFSH, estradiol 17-beta (E2), and progesterone values were determined before and during treatment. No consistent pretreatment hormonal pattern was found. During treatment hPRL levels fell in 13 of 14 patients, and E2 rose in 12 of 14 patients. Levels of hLH became normal, and amounts of hFSH did not change. Galactorrhea lessened in all cases and ceased in 11. Menses resumed in 11 patients and 3 women became pregnant. Cessation of galactorrhea and resumption of menses occurred irrespective of initial hPRL or hLH levels. It is suggested that improvement of galactorrhea and resumption of menses in some patients with normal hPRL values are the result of increased serum E2 levels and may be due to a direct action of bromo-ergocryptine on the ovary. Bromo-ergocryptine may also be effective in treatment of amenorrhea, unassociated with galactorrhea or elevated hPRL levels.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

934580

Citation

Dickey, R P., and S C. Stone. "Effect of Bromo-ergocryptine On Serum hPRL, hLH, hFSH, and Estradiol 17-beta in Women With Galactorrhea-amenorrhea." Obstetrics and Gynecology, vol. 48, no. 1, 1976, pp. 84-9.
Dickey RP, Stone SC. Effect of bromo-ergocryptine on serum hPRL, hLH, hFSH, and estradiol 17-beta in women with galactorrhea-amenorrhea. Obstet Gynecol. 1976;48(1):84-9.
Dickey, R. P., & Stone, S. C. (1976). Effect of bromo-ergocryptine on serum hPRL, hLH, hFSH, and estradiol 17-beta in women with galactorrhea-amenorrhea. Obstetrics and Gynecology, 48(1), 84-9.
Dickey RP, Stone SC. Effect of Bromo-ergocryptine On Serum hPRL, hLH, hFSH, and Estradiol 17-beta in Women With Galactorrhea-amenorrhea. Obstet Gynecol. 1976;48(1):84-9. PubMed PMID: 934580.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of bromo-ergocryptine on serum hPRL, hLH, hFSH, and estradiol 17-beta in women with galactorrhea-amenorrhea. AU - Dickey,R P, AU - Stone,S C, PY - 1976/7/1/pubmed PY - 1976/7/1/medline PY - 1976/7/1/entrez SP - 84 EP - 9 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 48 IS - 1 N2 - Fourteen women with amenorrhea-galactorrhea were treated with bromo-ergocryptine. Serum prolactin hPRL, hLH, hFSH, estradiol 17-beta (E2), and progesterone values were determined before and during treatment. No consistent pretreatment hormonal pattern was found. During treatment hPRL levels fell in 13 of 14 patients, and E2 rose in 12 of 14 patients. Levels of hLH became normal, and amounts of hFSH did not change. Galactorrhea lessened in all cases and ceased in 11. Menses resumed in 11 patients and 3 women became pregnant. Cessation of galactorrhea and resumption of menses occurred irrespective of initial hPRL or hLH levels. It is suggested that improvement of galactorrhea and resumption of menses in some patients with normal hPRL values are the result of increased serum E2 levels and may be due to a direct action of bromo-ergocryptine on the ovary. Bromo-ergocryptine may also be effective in treatment of amenorrhea, unassociated with galactorrhea or elevated hPRL levels. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/934580/Effect_of_bromo_ergocryptine_on_serum_hPRL_hLH_hFSH_and_estradiol_17_beta_in_women_with_galactorrhea_amenorrhea_ DB - PRIME DP - Unbound Medicine ER -