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Associations with intraocular pressure in the Barbados Eye Study.
Arch Ophthalmol 1997; 115(12):1572-6AO

Abstract

OBJECTIVE

To evaluate the demographic, medical, ocular, familial, and other factors possibly associated with intraocular pressure (IOP) in a black population, after excluding persons with any type of glaucoma.

DESIGN

The Barbados Eye Study was a population-based study of a random sample of residents of Barbados, West Indies, aged 40 to 84 years.

PARTICIPANTS

A subset of the Barbados Eye Study population consisting of 3752 black Barbados Eye Study participants without glaucoma.

DATA COLLECTION

A standardized protocol included applanation tonometry and other ocular data, blood pressure measurements, anthropometry, complexion pigmentation gradings, and a comprehensive interview.

MAIN OUTCOME MEASURE

Intraocular pressure was based on the average of 3 measurements at the Barbados Eye Study visit. Multiple linear regression was used to evaluate factors associated with IOP.

RESULTS

Systolic blood pressure (or hypertension), diabetes history, and age were the major factors positively associated with IOP (P<.01). Other positively related factors were female gender, darker complexion, pulse rate, higher body mass, seasonality, family history of glaucoma, current alcohol use, and current smoking. These factors explained 10% of the variation in IOP.

CONCLUSIONS

By identifying risk factors, these results define specific subgroups most likely to have an elevated IOP. The high IOP in this population may be linked to the high prevalence of hypertension and diabetes. Aside from age and a family history of glaucoma, none of the risk factors for high IOP evaluated in this study was similar to those associated with open-angle glaucoma.

Authors+Show Affiliations

Department of Preventive Medicine, University Medical Center at Stony Brook, NY 11794-8036, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

9400792

Citation

Wu, S Y., and M C. Leske. "Associations With Intraocular Pressure in the Barbados Eye Study." Archives of Ophthalmology (Chicago, Ill. : 1960), vol. 115, no. 12, 1997, pp. 1572-6.
Wu SY, Leske MC. Associations with intraocular pressure in the Barbados Eye Study. Arch Ophthalmol. 1997;115(12):1572-6.
Wu, S. Y., & Leske, M. C. (1997). Associations with intraocular pressure in the Barbados Eye Study. Archives of Ophthalmology (Chicago, Ill. : 1960), 115(12), pp. 1572-6.
Wu SY, Leske MC. Associations With Intraocular Pressure in the Barbados Eye Study. Arch Ophthalmol. 1997;115(12):1572-6. PubMed PMID: 9400792.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Associations with intraocular pressure in the Barbados Eye Study. AU - Wu,S Y, AU - Leske,M C, PY - 1997/12/24/pubmed PY - 1997/12/24/medline PY - 1997/12/24/entrez SP - 1572 EP - 6 JF - Archives of ophthalmology (Chicago, Ill. : 1960) JO - Arch. Ophthalmol. VL - 115 IS - 12 N2 - OBJECTIVE: To evaluate the demographic, medical, ocular, familial, and other factors possibly associated with intraocular pressure (IOP) in a black population, after excluding persons with any type of glaucoma. DESIGN: The Barbados Eye Study was a population-based study of a random sample of residents of Barbados, West Indies, aged 40 to 84 years. PARTICIPANTS: A subset of the Barbados Eye Study population consisting of 3752 black Barbados Eye Study participants without glaucoma. DATA COLLECTION: A standardized protocol included applanation tonometry and other ocular data, blood pressure measurements, anthropometry, complexion pigmentation gradings, and a comprehensive interview. MAIN OUTCOME MEASURE: Intraocular pressure was based on the average of 3 measurements at the Barbados Eye Study visit. Multiple linear regression was used to evaluate factors associated with IOP. RESULTS: Systolic blood pressure (or hypertension), diabetes history, and age were the major factors positively associated with IOP (P<.01). Other positively related factors were female gender, darker complexion, pulse rate, higher body mass, seasonality, family history of glaucoma, current alcohol use, and current smoking. These factors explained 10% of the variation in IOP. CONCLUSIONS: By identifying risk factors, these results define specific subgroups most likely to have an elevated IOP. The high IOP in this population may be linked to the high prevalence of hypertension and diabetes. Aside from age and a family history of glaucoma, none of the risk factors for high IOP evaluated in this study was similar to those associated with open-angle glaucoma. SN - 0003-9950 UR - https://www.unboundmedicine.com/medline/citation/9400792/Associations_with_intraocular_pressure_in_the_Barbados_Eye_Study_ L2 - https://jamanetwork.com/journals/jamaophthalmology/fullarticle/vol/115/pg/1572 DB - PRIME DP - Unbound Medicine ER -