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Caffeine withdrawal symptoms following brief caffeine deprivation.
Physiol Behav 1997; 63(1):35-9PB

Abstract

The effects of short-term caffeine deprivation on mood, withdrawal symptoms and psychomotor performance were studied in habitual coffee drinkers. Thirty-one male and female coffee drinkers were tested twice at midday (1130 to 1330 h) 4 h after double-blind administration of 250 mg of caffeine or placebo. Mood and withdrawal symptoms reports were collected by questionnaires. Psychomotor performance was tested with a brief computerized test battery, and causal blood pressure was measured. Caffeine deprivation was associated with decreased vigor and increased fatigue and with symptoms including sleepiness and yawning. Blood pressure was lower by 5-6 mm Hg. No changes in psychomotor performance were observed. Even short periods of caffeine deprivation, equivalent in length to missing regular morning coffee, can produce noticeable unpleasant caffeine withdrawal symptoms in habitual coffee drinkers. Such symptoms may be common side effects of habitual caffeine consumption that contribute to the maintenance of this behavior.

Authors+Show Affiliations

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.No affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

9402612

Citation

Phillips-Bute, B G., and J D. Lane. "Caffeine Withdrawal Symptoms Following Brief Caffeine Deprivation." Physiology & Behavior, vol. 63, no. 1, 1997, pp. 35-9.
Phillips-Bute BG, Lane JD. Caffeine withdrawal symptoms following brief caffeine deprivation. Physiol Behav. 1997;63(1):35-9.
Phillips-Bute, B. G., & Lane, J. D. (1997). Caffeine withdrawal symptoms following brief caffeine deprivation. Physiology & Behavior, 63(1), pp. 35-9.
Phillips-Bute BG, Lane JD. Caffeine Withdrawal Symptoms Following Brief Caffeine Deprivation. Physiol Behav. 1997 Dec 31;63(1):35-9. PubMed PMID: 9402612.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Caffeine withdrawal symptoms following brief caffeine deprivation. AU - Phillips-Bute,B G, AU - Lane,J D, PY - 1997/12/24/pubmed PY - 1997/12/24/medline PY - 1997/12/24/entrez SP - 35 EP - 9 JF - Physiology & behavior JO - Physiol. Behav. VL - 63 IS - 1 N2 - The effects of short-term caffeine deprivation on mood, withdrawal symptoms and psychomotor performance were studied in habitual coffee drinkers. Thirty-one male and female coffee drinkers were tested twice at midday (1130 to 1330 h) 4 h after double-blind administration of 250 mg of caffeine or placebo. Mood and withdrawal symptoms reports were collected by questionnaires. Psychomotor performance was tested with a brief computerized test battery, and causal blood pressure was measured. Caffeine deprivation was associated with decreased vigor and increased fatigue and with symptoms including sleepiness and yawning. Blood pressure was lower by 5-6 mm Hg. No changes in psychomotor performance were observed. Even short periods of caffeine deprivation, equivalent in length to missing regular morning coffee, can produce noticeable unpleasant caffeine withdrawal symptoms in habitual coffee drinkers. Such symptoms may be common side effects of habitual caffeine consumption that contribute to the maintenance of this behavior. SN - 0031-9384 UR - https://www.unboundmedicine.com/medline/citation/9402612/Caffeine_withdrawal_symptoms_following_brief_caffeine_deprivation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-9384(97)00384-3 DB - PRIME DP - Unbound Medicine ER -