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Drug treatment of migraine: Part II. Preventive therapy.
Am Fam Physician. 1997 Dec; 56(9):2279-86.AF

Abstract

In most cases, successful preventive therapy for migraines requires daily medication for months or years. Perimenstrual use of a preventive agent is a common exception. Preventive therapy is usually undertaken in patients who have more than two headache episodes per month or those very much disabled by headaches. Beta blockers are usually the first choice for preventive therapy, and amitriptyline is also commonly used. Despite widespread use of calcium channel blockers for prevention of migraine, their benefits are controversial. Although effective for prevention of migraine, methysergide and phenelzine are usually relegated to last-resort use because of potentially serious side effects. The migraine patient who is refractory to standard preventive therapy may have rebound headache related to overuse of abortive migraine medications, or concomitant psychopathology.

Authors+Show Affiliations

University of Mississippi Medical Center, Jackson, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9402813

Citation

Noble, S L., and K L. Moore. "Drug Treatment of Migraine: Part II. Preventive Therapy." American Family Physician, vol. 56, no. 9, 1997, pp. 2279-86.
Noble SL, Moore KL. Drug treatment of migraine: Part II. Preventive therapy. Am Fam Physician. 1997;56(9):2279-86.
Noble, S. L., & Moore, K. L. (1997). Drug treatment of migraine: Part II. Preventive therapy. American Family Physician, 56(9), 2279-86.
Noble SL, Moore KL. Drug Treatment of Migraine: Part II. Preventive Therapy. Am Fam Physician. 1997;56(9):2279-86. PubMed PMID: 9402813.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drug treatment of migraine: Part II. Preventive therapy. AU - Noble,S L, AU - Moore,K L, PY - 1997/12/24/pubmed PY - 1997/12/24/medline PY - 1997/12/24/entrez SP - 2279 EP - 86 JF - American family physician JO - Am Fam Physician VL - 56 IS - 9 N2 - In most cases, successful preventive therapy for migraines requires daily medication for months or years. Perimenstrual use of a preventive agent is a common exception. Preventive therapy is usually undertaken in patients who have more than two headache episodes per month or those very much disabled by headaches. Beta blockers are usually the first choice for preventive therapy, and amitriptyline is also commonly used. Despite widespread use of calcium channel blockers for prevention of migraine, their benefits are controversial. Although effective for prevention of migraine, methysergide and phenelzine are usually relegated to last-resort use because of potentially serious side effects. The migraine patient who is refractory to standard preventive therapy may have rebound headache related to overuse of abortive migraine medications, or concomitant psychopathology. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/9402813/Drug_treatment_of_migraine:_Part_II__Preventive_therapy_ L2 - http://www.diseaseinfosearch.org/result/4811 DB - PRIME DP - Unbound Medicine ER -